Frietze Gabriel A, Xu Cai, Mancera Bibiana, Robles-Escajeda Elisa, Martinez Alyssa A, Gil Michelle, Flores Diana P, Begum Khodeza, Liang Panfeng, Mandal Abhijit, Nsiah-Nimo Michael, Sanyal Nilotpal, Leung Ming-Ying, Kenney Michael J, Kirken Robert A
Border Biomedical Research Center, College of Science, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.
Int J Environ Res Public Health. 2025 Apr 20;22(4):647. doi: 10.3390/ijerph22040647.
Hispanic adults have an increased incidence of type 2 diabetes (T2D) at a younger age and diagnosis of certain cancers, including liver, stomach, and colorectal, which may be attributed to metabolic health. Several key metabolic health indicators, such as hemoglobin A1c (HbA1c), body mass index (BMI), and waist-to-hip ratio (WHR), have been linked to obesity. The purpose of this pilot study was to explore the complex relationships between socio-behavioral factors that lead to the increased incidence of metabolic syndrome (e.g., HbA1c) and chronic inflammation (interleukins) in Hispanics. Two hundred and twelve Hispanic participants ( = 43.45, = 15.36) who identified predominantly as female (72.17%) were included in the study. Correlational analyses revealed that HbA1c was positively associated with age and negatively associated with several socio-behavioral factors, including overall health, quality of life, physical health, physical performance, social support, mother's education, and father's education. These findings highlight the importance of social support and parental involvement in diabetes management. The focused integration of socio-behavioral and biological data provides a powerful foundation for future research and the development of targeted interventions.
西班牙裔成年人患2型糖尿病(T2D)的发病率在年轻时就有所增加,并且某些癌症的诊断率也较高,包括肝癌、胃癌和结直肠癌,这可能归因于代谢健康。一些关键的代谢健康指标,如糖化血红蛋白(HbA1c)、体重指数(BMI)和腰臀比(WHR),都与肥胖有关。这项初步研究的目的是探讨导致西班牙裔人群代谢综合征(如HbA1c)发病率增加的社会行为因素与慢性炎症(白细胞介素)之间的复杂关系。该研究纳入了212名西班牙裔参与者(平均年龄43.45岁,标准差15.36),其中女性占主导地位(72.17%)。相关性分析显示,HbA1c与年龄呈正相关,与几个社会行为因素呈负相关,这些因素包括总体健康状况、生活质量、身体健康、身体机能、社会支持、母亲的教育程度和父亲的教育程度。这些发现凸显了社会支持和父母参与在糖尿病管理中的重要性。社会行为数据和生物学数据的重点整合为未来的研究和有针对性的干预措施的开发提供了有力的基础。