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Neurobiological Implications of Chronic Stress and Metabolic Dysregulation in Inflammatory Bowel Diseases.慢性应激与代谢失调在炎症性肠病中的神经生物学影响
Diseases. 2024 Sep 18;12(9):220. doi: 10.3390/diseases12090220.
2
Association between glucose levels of children with type 1 diabetes and parental economic status in mobile health application.移动健康应用中1型糖尿病儿童血糖水平与父母经济状况之间的关联
World J Diabetes. 2024 Jul 15;15(7):1477-1488. doi: 10.4239/wjd.v15.i7.1477.
3
Sustained metabolic dysregulation and the emergence of diabetes: associations between HbA1c and metabolic syndrome components in Tunisian diabetic and nondiabetic groups.持续的代谢失调与糖尿病的出现:HbA1c 与突尼斯糖尿病和非糖尿病组代谢综合征成分之间的关系。
J Physiol Anthropol. 2024 Jul 20;43(1):18. doi: 10.1186/s40101-024-00365-4.
4
Relationship between social isolation and glycaemic control of people previously diagnosed with diabetes: secondary analysis from the CHARLS.社会隔离与既往诊断糖尿病患者血糖控制的关系:CHARLS 的二次分析。
BMJ Open. 2024 Mar 19;14(3):e076106. doi: 10.1136/bmjopen-2023-076106.
5
Trends of HbA1c and BMI in People with Type 2 Diabetes: A Japanese Claims-Based Study.2型糖尿病患者糖化血红蛋白(HbA1c)和体重指数(BMI)的变化趋势:一项基于日本医保理赔数据的研究
Diabetes Ther. 2024 Apr;15(4):801-817. doi: 10.1007/s13300-024-01543-4. Epub 2024 Feb 24.
6
Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review.感染性疾病中的促炎和抗炎白细胞介素:综述
Trop Med Infect Dis. 2024 Jan 4;9(1):13. doi: 10.3390/tropicalmed9010013.
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The effect of age and gender on HbA1c levels in adults without diabetes mellitus.年龄和性别对无糖尿病成年人糖化血红蛋白(HbA1c)水平的影响。
J Med Biochem. 2023 Oct 27;42(4):714-721. doi: 10.5937/jomb0-44190.
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Value of waist-to-hip ratio as a predictor of metabolic syndrome in adolescents with obesity.腰臀比作为肥胖青少年代谢综合征预测指标的价值。
Acta Biomed. 2023 Jun 14;94(3):e2023076. doi: 10.23750/abm.v94i3.13755.
9
The crucial role and mechanism of insulin resistance in metabolic disease.胰岛素抵抗在代谢性疾病中的关键作用及其机制。
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The relationship between well-being and HbA1c in adults with type 1 diabetes: A systematic review.1 型糖尿病成人的幸福感与 HbA1c 之间的关系:系统评价。
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在美国/墨西哥边境沿线居住的大学样本中探索代谢和炎症风险的社会行为相关因素:一项同时收集调查数据、血液和头发样本以及身体测量数据的试点研究。

Exploring Socio-Behavioral Correlates of Metabolic and Inflammatory Risk in a University Sample Residing Along the U.S./Mexico Border: A Pilot Study Concomitantly Collecting Survey Data, Blood and Hair Samples, and Physical Measures.

作者信息

Frietze Gabriel A, Xu Cai, Mancera Bibiana, Robles-Escajeda Elisa, Martinez Alyssa A, Gil Michelle, Flores Diana P, Begum Khodeza, Liang Panfeng, Mandal Abhijit, Nsiah-Nimo Michael, Sanyal Nilotpal, Leung Ming-Ying, Kenney Michael J, Kirken Robert A

机构信息

Border Biomedical Research Center, College of Science, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.

出版信息

Int J Environ Res Public Health. 2025 Apr 20;22(4):647. doi: 10.3390/ijerph22040647.

DOI:10.3390/ijerph22040647
PMID:40283868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12026700/
Abstract

Hispanic adults have an increased incidence of type 2 diabetes (T2D) at a younger age and diagnosis of certain cancers, including liver, stomach, and colorectal, which may be attributed to metabolic health. Several key metabolic health indicators, such as hemoglobin A1c (HbA1c), body mass index (BMI), and waist-to-hip ratio (WHR), have been linked to obesity. The purpose of this pilot study was to explore the complex relationships between socio-behavioral factors that lead to the increased incidence of metabolic syndrome (e.g., HbA1c) and chronic inflammation (interleukins) in Hispanics. Two hundred and twelve Hispanic participants ( = 43.45, = 15.36) who identified predominantly as female (72.17%) were included in the study. Correlational analyses revealed that HbA1c was positively associated with age and negatively associated with several socio-behavioral factors, including overall health, quality of life, physical health, physical performance, social support, mother's education, and father's education. These findings highlight the importance of social support and parental involvement in diabetes management. The focused integration of socio-behavioral and biological data provides a powerful foundation for future research and the development of targeted interventions.

摘要

西班牙裔成年人患2型糖尿病(T2D)的发病率在年轻时就有所增加,并且某些癌症的诊断率也较高,包括肝癌、胃癌和结直肠癌,这可能归因于代谢健康。一些关键的代谢健康指标,如糖化血红蛋白(HbA1c)、体重指数(BMI)和腰臀比(WHR),都与肥胖有关。这项初步研究的目的是探讨导致西班牙裔人群代谢综合征(如HbA1c)发病率增加的社会行为因素与慢性炎症(白细胞介素)之间的复杂关系。该研究纳入了212名西班牙裔参与者(平均年龄43.45岁,标准差15.36),其中女性占主导地位(72.17%)。相关性分析显示,HbA1c与年龄呈正相关,与几个社会行为因素呈负相关,这些因素包括总体健康状况、生活质量、身体健康、身体机能、社会支持、母亲的教育程度和父亲的教育程度。这些发现凸显了社会支持和父母参与在糖尿病管理中的重要性。社会行为数据和生物学数据的重点整合为未来的研究和有针对性的干预措施的开发提供了有力的基础。