Grecco Marcus Vinicius, Moura Dos Santos Alexandre, Greve JúliaMaria D'Andrea, Alonso Angélica Castilho, Afonso Mara Silvia, de Sousa Juliana Cristina, Quintana Marília Simões Lopes, Soares-Junior José Maria, Baracat Edmund Chada, Brech Guilherme Carlos, Silva Paulo Roberto Santos
Laboratory Study of Movement, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; Sports Medicine Division, Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP), São Paulo, SP, Brazil; FIFA Medical Centre of Excellence, São Paulo, SP, Brazil.
Department of Rheumatology at Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Clinics (Sao Paulo). 2025 Apr 25;80:100614. doi: 10.1016/j.clinsp.2025.100614. eCollection 2025.
To verify the effect of 12 weeks of Combined Training (CT) in patients suffering from COVID-19 of mild to moderate intensity.
69 participants diagnosed with mild to moderate COVID-19 were evaluated, with shortness of breath as the main symptom. All of them were sent by the Centro de Atendimento ao Funcionário do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (CEAC-HCFMUSP). The sample was divided into three groups: Group 1 (G1) - 26 patients diagnosed with COVID-19 evaluated before and after combined training together with nutritional guidance. Group 2 (G2) - 21 patients diagnosed with COVID-19 were evaluated before and after 12 weeks. Patients in G2 (control) did not participate in the protocol but were instructed to train outside the hospital and did not receive nutritional guidance. Group 3 (G3) - 22 patients diagnosed with COVID-19 were evaluated before and after combined training along with nutritional monitoring and post-workout whey protein supplementation throughout the duration of the protocol.
The three groups did not have significant statistical differences when compared to each other, but there was significant intragroup improvement in the analyzed variables. There was an improvement in cardiorespiratory, metabolic, and muscular fitness. Furthermore, late symptoms of the disease were reduced at the end of the program.
The results of the dependent variables analyzed were significant within groups, CT was an efficient training model in improving the patient's general condition (fatigue and dyspnea) when training was controlled with supervision.
验证为期12周的联合训练（CT）对轻至中度新型冠状病毒肺炎（COVID-19）患者的效果。
对69名被诊断为轻至中度COVID-19且以呼吸急促为主要症状的参与者进行评估。他们均由圣保罗大学医学院临床医院员工护理中心（CEAC-HCFMUSP）送来。样本分为三组：第1组（G1）-26名被诊断为COVID-19的患者在接受联合训练及营养指导前后接受评估。第2组（G2）-21名被诊断为COVID-19的患者在12周前后接受评估。G2组（对照组）患者未参与该方案，但被指示在医院外进行训练，且未接受营养指导。第3组（G3）-22名被诊断为COVID-19的患者在接受联合训练及营养监测，并在整个方案期间补充运动后乳清蛋白前后接受评估。
三组相互比较时无显著统计学差异，但各分析变量在组内有显著改善。心肺功能、代谢和肌肉适应性均有改善。此外，在项目结束时疾病的后期症状有所减轻。
所分析的因变量结果在组内具有显著性，当训练在监督下进行控制时，联合训练是改善患者总体状况（疲劳和呼吸困难）的有效训练模式。
