Nikel Kamil, Stojko Michał, Smolarczyk Joanna, Piegza Magdalena
Students Scientific Association, Department of Psychiatry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Department of Psychoprophylaxis, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Nutrients. 2025 Mar 7;17(6):933. doi: 10.3390/nu17060933.
The gut microbiota plays a key role in mental health, with growing evidence linking its composition to anxiety and depressive disorders. Research on this topic has expanded significantly in recent years. This review explores alterations in the gut microbiota of individuals with anxiety disorders and examines the potential therapeutic effects of probiotics. : This review aims to analyze the alterations in gut microbiota composition in individuals with anxiety disorders and evaluate the potential therapeutic effects of probiotics in mitigating symptoms. By examining recent research, this study seeks to highlight the gut-brain connection and its implications for mental health interventions. : A literature search was conducted in PubMed, Embase, CINAHL, and Google Scholar, focusing on studies investigating the relationship between gut microbiota and anxiety disorders, as well as the impact of probiotics on symptom severity. : The reviewed studies suggest that individuals with anxiety disorders often exhibit gut microbiota alterations, including reduced microbial diversity and a lower abundance of short-chain fatty acid-producing bacteria. Additionally, probiotics, particularly those from the , may help alleviate anxiety symptoms by modulating gut microbiota composition. : Gut dysbiosis appears to be closely linked to anxiety disorders, and probiotic interventions could represent a promising therapeutic avenue. However, further research is needed to clarify underlying mechanisms and optimize treatment strategies.
肠道微生物群在心理健康中起着关键作用，越来越多的证据表明其组成与焦虑症和抑郁症有关。近年来，关于这一主题的研究显著扩展。本综述探讨了焦虑症患者肠道微生物群的变化，并研究了益生菌的潜在治疗作用。：本综述旨在分析焦虑症患者肠道微生物群组成的变化，并评估益生菌在减轻症状方面的潜在治疗效果。通过审视近期研究，本研究旨在突出肠道与大脑的联系及其对心理健康干预的意义。：在PubMed、Embase、CINAHL和谷歌学术上进行了文献检索，重点关注调查肠道微生物群与焦虑症之间关系以及益生菌对症状严重程度影响的研究。：综述的研究表明，焦虑症患者通常表现出肠道微生物群的变化，包括微生物多样性降低和产生短链脂肪酸的细菌丰度降低。此外，益生菌，特别是来自 的益生菌，可能通过调节肠道微生物群组成来帮助减轻焦虑症状。：肠道生态失调似乎与焦虑症密切相关，益生菌干预可能是一条有前景的治疗途径。然而，需要进一步研究以阐明潜在机制并优化治疗策略。
