O'Gorman Ellen, Varanasi Swathi, Bukoski Scott, Mitschke Susanne, Conger Scott
Clinical Research, Citruslabs, Las Vegas, USA.
Cureus. 2025 Mar 26;17(3):e81244. doi: 10.7759/cureus.81244. eCollection 2025 Mar.
The purpose of this study was to investigate the efficacy of a commercially available manuka honey-based face serum that includes royal jelly and bee venom on various ingredients frequently associated with skin health benefits over an eight-week period.
Forty female participants aged 40-55 with self-reported skin health concerns were recruited. Participants used the serum twice daily and completed questionnaires during Weeks 2, 4, and 8. Photos of the face were analyzed for dermatological skin grading and Optic Elite facial analysis at Week 8.
There were significant improvements in fine lines, wrinkles, dark spots, hyperpigmentation, dryness, and overall skin health beginning at Week 2, with sustained enhancements observed until Week 8. Dermatologist skin grading results were mixed, with 20 (60.6%) of participants demonstrating improvements in skin brightness, but lower percentages of participants showed improvement in overall skin health, fine lines/wrinkles, roughness, pigmentation, and redness/erythema. Optic Elite analysis showed improvements in several skin health scores, providing further evidence for the serum's effects on skin health. Participants self-reported high satisfaction with the effectiveness of the serum.
These findings suggest that the face serum may be an effective skincare product for improving skin health and mitigating signs of aging.
本研究旨在调查一种市售的含蜂王浆和蜂毒的麦卢卡蜂蜜面部精华液在八周时间内对各种与皮肤健康益处相关的成分的功效。
招募了40名年龄在40 - 55岁之间、自我报告有皮肤健康问题的女性参与者。参与者每天使用两次该精华液，并在第2周、第4周和第8周完成问卷调查。在第8周时，对面部照片进行皮肤学分级分析和Optic Elite面部分析。
从第2周开始，细纹、皱纹、黑斑、色素沉着、干燥和整体皮肤健康状况均有显著改善，直至第8周持续增强。皮肤科医生的皮肤分级结果不一，20名（60.6%）参与者的皮肤亮度有所改善，但在整体皮肤健康、细纹/皱纹、粗糙度、色素沉着和发红/红斑方面显示改善的参与者比例较低。Optic Elite分析显示几个皮肤健康评分有所改善，为该精华液对皮肤健康的作用提供了进一步证据。参与者自我报告对该精华液的有效性高度满意。
这些发现表明，该面部精华液可能是一种有效的护肤品，可改善皮肤健康并减轻衰老迹象。
