Xu Chen, Zhang Chuanhui, Xu Shu, Ma Jingli, Ran Lingling
Department of Obstetrics and Gynecology, Chaoyang Central Hospital, Chaoyang City, Liaoning Province, China.
Department of Joint and Sports Medicine, Chaoyang Central Hospital, Chaoyang City, Liaoning Province, China.
Medicine (Baltimore). 2025 Apr 25;104(17):e42014. doi: 10.1097/MD.0000000000042014.
Infertility is a significant global reproductive health challenge with varying prevalence across regions. While assisted reproductive technologies, especially in vitro fertilization, have created new possibilities for treating infertility, embryo transfer success remains limited by multiple factors, particularly endometrial receptivity. Understanding the relationship between embryo transfer and endometrial receptivity is crucial for advancing reproductive medicine and improving infertility treatment outcomes. To address the lack of bibliometric analysis in this field, we conducted a comprehensive bibliometric study of relevant academic literature.
We analyzed articles and reviews on endometrial receptivity and embryo transfer from the Web of Science Core Collection using CiteSpace, VOSviewer, and Bibliometrix package. The analysis focused on countries, institutions, journals, authors, keywords, and references.
We identified 1478 documents published over 2 decades, showing an upward trend in annual publications. China led in publication volume, while the USA had the highest citation impact. The University of Valencia and Shanghai Jiao Tong University were the most productive institutions, with fertility and sterility being the leading journal. Simón, C emerged as the most influential author based on publication count and citations. Key research areas included comparing fresh versus frozen embryo transfer, addressing repeated implantation failure, and improving endometrial receptivity. The endometrial receptivity array for personalized embryo transfer represents an emerging research direction in reproductive medicine.
This first comprehensive bibliometric analysis of embryo transfer and endometrial receptivity research provides valuable insights into knowledge development, research hotspots, and future directions in the field, serving as a crucial reference for scholars in reproductive medicine.
不孕症是一项重大的全球生殖健康挑战,不同地区的患病率各不相同。虽然辅助生殖技术,尤其是体外受精,为治疗不孕症创造了新的可能性,但胚胎移植的成功率仍然受到多种因素的限制,特别是子宫内膜容受性。了解胚胎移植与子宫内膜容受性之间的关系对于推进生殖医学和改善不孕症治疗结果至关重要。为了解决该领域缺乏文献计量分析的问题,我们对相关学术文献进行了全面的文献计量研究。
我们使用CiteSpace、VOSviewer和Bibliometrix软件包分析了来自科学网核心合集关于子宫内膜容受性和胚胎移植的文章及综述。分析聚焦于国家、机构、期刊、作者、关键词和参考文献。
我们识别出20多年来发表的1478篇文献,显示出年发表量呈上升趋势。中国在发表量上领先,而美国的被引影响力最高。巴伦西亚大学和上海交通大学是产出最多的机构,《生育与不孕》是领先期刊。基于发表数量和引用情况,西蒙·C成为最具影响力的作者。关键研究领域包括比较新鲜胚胎移植与冷冻胚胎移植、解决反复种植失败问题以及改善子宫内膜容受性。个性化胚胎移植的子宫内膜容受性阵列代表了生殖医学中一个新兴的研究方向。
这项首次对胚胎移植和子宫内膜容受性研究进行的全面文献计量分析为该领域的知识发展、研究热点和未来方向提供了有价值的见解,为生殖医学领域的学者提供了重要参考。