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病毒感染的遗传毒性后果。

Genotoxic consequences of viral infections.

作者信息

Szewczyk-Roszczenko Olga, Roszczenko Piotr, Vassetzky Yegor, Sjakste Nikolajs

机构信息

Department of Synthesis and Technology of Drugs, Medical University of Bialystok, Bialystok, Poland.

Department of Biotechnology, Medical University of Bialystok, Bialystok, Poland.

出版信息

Npj Viruses. 2025 Jan 27;3(1):5. doi: 10.1038/s44298-024-00087-5.

DOI:10.1038/s44298-024-00087-5
PMID:40295867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11772741/
Abstract

Viral diseases continually threaten human health as evolving pathogens introduce new risks. These infections can lead to complications across organ systems, with impacts varying by virus type, infection severity, and individual immune response. This review examines the genotoxic stress caused by viral infections and its pathological consequences in humans.

摘要

随着不断进化的病原体带来新的风险，病毒性疾病持续威胁着人类健康。这些感染可导致全身各器官系统出现并发症，其影响因病毒类型、感染严重程度和个体免疫反应而异。本文综述了病毒感染引起的基因毒性应激及其对人类的病理后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30d/11772741/886d637e1f71/44298_2024_87_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30d/11772741/6c69f087791e/44298_2024_87_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30d/11772741/886d637e1f71/44298_2024_87_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30d/11772741/6c69f087791e/44298_2024_87_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30d/11772741/886d637e1f71/44298_2024_87_Fig2_HTML.jpg

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[1]
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[2]
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[3]
Epigenetic Mechanisms in Latent Epstein-Barr Virus Infection and Associated Cancers.

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[4]
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[5]
Specificity of cancer-related chromosomal translocations is linked to proximity after the DNA double-strand break and subsequent selection.

NAR Cancer. 2023-9-23

[6]
Long-term complications after infection with SARS-CoV-1, influenza and MERS-CoV - Lessons to learn in long COVID?

Infect Dis Now. 2023-10

[7]
Oncoviruses: How do they hijack their host and current treatment regimes.

Biochim Biophys Acta Rev Cancer. 2023-9

[8]
The complementarity of DDR, nucleic acids and anti-tumour immunity.

Nature. 2023-7

[9]
Oxidative stress, DNA damage, and inflammation in COVID-19 patients.

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[10]
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