Mahmood Lina, Sarkar Kasturi R, Neal Kaymon, Brown Rita C, Brown Andrew W, Stewart Scott, Pesek Robert D, Jefferson Akilah A, Perry Tamara T
Department of Pediatric Allergy and Immunology, and Arkansas Children's Research Institute, University of Arkansas for Medical Sciences/Arkansas Children's Hospital, Little Rock, AR, USA.
Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
J Asthma. 2025 Sep;62(9):1591-1598. doi: 10.1080/02770903.2025.2499829. Epub 2025 May 5.
To assess the feasibility of at-home video directly observed therapy (vDOT) among pediatric patients with asthma to learn and retain proper inhaler technique.
We conducted a randomized pilot study with 22 children with persistent asthma aged 6-11 years who were newly prescribed an asthma controller inhaler. Patients underwent 1:1 randomization into one group receiving standard inhaler education during clinic and another receiving standard education plus vDOT for 30 days. vDOT is a method by which trained professionals observe patients self-administering medications through a virtual platform to monitor adherence and proper medication use. We measured inhaler technique, age-appropriate Asthma Control Test (ACT) score, symptom-free days, and healthcare utilization in both groups at 3 months.
Median inhaler technique accuracy percentage score was 88% (IQR 66, 100) for vDOT participants compared to 75% (IQR 38, 88) for controls ( = 0.11). Technique errors within the vDOT group included inadequate breath-holding (34%), inadequate breathing technique (29%), incorrect/no shaking of inhaler (22%) and failure to rinse mouth (15%). There was no difference between groups in change in ACT score, resource utilization or controller prescription refill rates. In the first 30 days, the median number of days until vDOT participants had no observed technique errors was 10 days (range 0-25).
vDOT is a viable technique to provide initial and continual education and real-time feedback on inhaler technique after the initial education provided in clinic.
评估家庭视频直接观察疗法(vDOT)在哮喘患儿中学习和保持正确吸入器技术的可行性。
我们对22名年龄在6至11岁、新开具哮喘控制吸入器处方的持续性哮喘儿童进行了一项随机试点研究。患者被1:1随机分为两组,一组在诊所接受标准吸入器教育,另一组在接受标准教育的基础上再接受30天的vDOT。vDOT是一种由经过培训的专业人员通过虚拟平台观察患者自我给药,以监测依从性和正确用药情况的方法。我们在3个月时测量了两组的吸入器技术、适合年龄的哮喘控制测试(ACT)评分、无症状天数和医疗保健利用率。
vDOT参与者的吸入器技术准确率中位数为88%(四分位间距66, 100),而对照组为75%(四分位间距38, 88)(P = 0.11)。vDOT组内的技术错误包括屏气不足(34%)、呼吸技术不足(29%)、吸入器未正确摇晃/未摇晃(22%)和未漱口(15%)。两组在ACT评分变化、资源利用或控制剂处方 refill率方面没有差异。在最初的30天里,vDOT参与者直到未观察到技术错误的天数中位数为10天(范围0至25天)。
vDOT是一种可行的技术,可在诊所提供初始教育后,就吸入器技术提供初始和持续教育以及实时反馈。