Aurias A, Couturier J, Dutrillaux A M, Dutrillaux B, Herpin F, Lamoliatte E, Lombard M, Muleris M, Paravatou M, Prieur M
Hum Genet. 1985;71(1):19-21. doi: 10.1007/BF00295660.
In a large study of chromosome rearrangements occurring in human lymphocytes from normal subjects, inv (14)(q12qter) or (q11.2q32.3) is found to be the most frequent, affecting 0.15% of mitoses. The same inversion is observed in the lymphocytes of the chimpanzee, indicating the ancestry of this inversion. It is not induced by ionizing radiations, and its frequency may be increased in Fanconi anemia, but not in ataxia telangiectasia. It may represent one of the steps of the process of leukemogenesis.
在一项对正常受试者人类淋巴细胞中发生的染色体重排的大型研究中，发现inv(14)(q12qter)或(q11.2q32.3)最为常见，影响0.15%的有丝分裂。在黑猩猩的淋巴细胞中也观察到相同的倒位，表明这种倒位的起源。它不是由电离辐射诱导的，在范可尼贫血中其频率可能会增加，但在共济失调毛细血管扩张症中不会。它可能代表白血病发生过程的步骤之一。
