Ashton G C
Hum Hered. 1985;35(4):232-9. doi: 10.1159/000153551.
Segregation analysis of ocular spherical refraction data using a unified model resulted in rejection of a Mendelian hypothesis of genetic transmission in nuclear families of both Japanese and European ancestries. Similar analyses of families which included at least 1 myope gave no evidence for the hypothesis that myopia is determined in part by a major gene. Most of the variation associated with ocular refraction, or with myopia, seems to be nongenetic in origin.
使用统一模型对眼屈光数据进行分离分析，结果否定了日本和欧洲血统核心家庭中孟德尔遗传传递假说。对至少包含1名近视患者的家庭进行的类似分析，没有为近视部分由一个主基因决定这一假说提供证据。与眼屈光或近视相关的大部分变异似乎起源于非遗传因素。
