Sadrzadeh Sayyed Majid, Talebzadeh Vahid, Mousavi Seyed Mohammad, Rezvani Kakhki Behrang, Vafadar Moradi Elnaz, Feiz Disfani Hamideh
Department of Emergency Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Emergency Medicine, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
Bull Emerg Trauma. 2025;13(1):32-36. doi: 10.30476/beat.2025.103125.1519.
This study aimed to investigate the prognostic role of lactate clearance in predicting outcomes among trauma patients admitted to the emergency department.
This retrospective cohort study was conducted on patients referred to the Emergency Department. Serum lactate levels were measured at admission and 2 hours later. The patients were followed up for 72 hours to assess outcomes, including discharge, hospitalization in other wards, and mortality.
The results showed a significant difference between the mean age, Glasgow Coma Scale (GCS), systolic blood pressure (SBP), pulse rate (PR), and oxygen saturation (O Sat) of the trauma patients in relation to mortality prognosis (<0.05). Additionally, significant differences were found in primary lactate, lactate levels two hours post-admission, and lactate clearance levels based on the patient's prognosis (<0.01). Multivariate logistic regression analysis revealed that lactate clearance was associated with a reduced mortality rate among trauma patients (OR=0.907, <0.05).
The findings of this study showed that lactate clearance, as an independent predictive factor, was associated with poorer prognosis and increased mortality rates in trauma patients.
本研究旨在探讨乳酸清除率在预测急诊科收治的创伤患者预后中的作用。
对转诊至急诊科的患者进行了这项回顾性队列研究。入院时及2小时后测量血清乳酸水平。对患者进行72小时随访,以评估结局,包括出院、转至其他病房住院及死亡率。
结果显示,创伤患者的平均年龄、格拉斯哥昏迷量表(GCS)、收缩压(SBP)、脉搏率(PR)和血氧饱和度(O Sat)在死亡率预后方面存在显著差异(<0.05)。此外,根据患者预后,原发性乳酸、入院后2小时乳酸水平和乳酸清除率水平也存在显著差异(<0.01)。多因素逻辑回归分析显示,乳酸清除率与创伤患者死亡率降低相关(OR=0.907,<0.05)。
本研究结果表明,乳酸清除率作为一个独立的预测因素,与创伤患者较差的预后和较高的死亡率相关。