Misra Akanksha, Wolfe Olivia, Azziz Ricardo
SUNY Plattsburgh, Plattsburgh, New York, USA.
Depts. of Obstetrics & Gynecology, Heersink School of Medicine, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.
Womens Health Rep (New Rochelle). 2025 Apr 10;6(1):412-420. doi: 10.1089/whr.2024.0130. eCollection 2025.
To determine associations of childhood emotional and physical abuse and neglect with the incidence of menstrual irregularity, male pattern hair growth, and possible PCOS.
Cross-sectional Study at University.
410 individuals, 18-45 years old.
Survey.
A questionnaire was administered to students, faculty, and staff at a regional State University of New York (SUNY) campus. Data on sociodemographic factors, menstrual dysfunction (irregularity, male pattern hair growth, and PCOS), and experiences of childhood abuse and neglect were collected.
Participants were sub-grouped into those with menstrual irregularity (MI: defined as >35 days between one period's beginning and the next, or ≤8 cycles/year, or absent periods altogether), or male pattern hair growth (MHG: defined as excess hair on the upper lip, chin, chest, abdomen, buttocks, or back), both (MI+MHG), or those who did have neither (Unaffected). Family income status yielded some association with the presence of MI, MHG, or MI+MHG. There were significant correlations between individuals reporting MI, MHG, and MI+MHG and reported experiences of feeling loved by their caregiver ( value = 0.0029988), experiencing verbal abuse ( value = 0.0000004293), experiencing physical neglect ( value = 0.030228), feeling emotionally disconnected from their caregiver ( value = 0.0006138), and not having a peaceful home ( value = 0.00005760630462), vis-à-vis Unaffected individuals. Almost all respondents with a prior diagnosis of PCOS (97.6%) reported MI and/or MHG.
All childhood experiences of abuse and neglect, except the loss of a parent, were significantly associated with features suggestive of PCOS. Larger, unbiased population studies across different demographics, are needed.
确定儿童期情感虐待、身体虐待及忽视与月经不调、男性型毛发增多以及可能的多囊卵巢综合征发病率之间的关联。
在大学开展的横断面研究。
410名年龄在18至45岁之间的个体。
调查。
对纽约州立大学（SUNY）一个地区校园的学生、教职员工进行问卷调查。收集社会人口学因素、月经功能障碍（月经不调、男性型毛发增多和多囊卵巢综合征）以及儿童期虐待和忽视经历的数据。
参与者被分为月经不调组（MI：定义为相邻两次月经开始时间间隔>35天，或每年月经周期≤8次，或完全闭经）、男性型毛发增多组（MHG：定义为上唇、下巴、胸部、腹部、臀部或背部毛发过多）、两者兼具组（MI+MHG）以及无上述情况组（未受影响组）。家庭收入状况与MI、MHG或MI+MHG的存在存在一定关联。报告有MI、MHG和MI+MHG的个体与报告感受到照顾者关爱的经历（值=0.0029988）、遭受言语虐待（值=0.0000004293）、遭受身体忽视（值=0.030228）、感觉与照顾者情感疏离（值=0.0006138）以及没有一个安宁的家（值=0.00005760630462）之间存在显著相关性，与未受影响个体相比。几乎所有先前被诊断为多囊卵巢综合征的受访者（97.6%）都报告有MI和/或MHG。
除了父母一方去世外，所有儿童期虐待和忽视经历都与提示多囊卵巢综合征的特征显著相关。需要在不同人口统计学特征的人群中开展更大规模、无偏倚的研究。
