Chervu Nikhil L, Mallick Saad, Vadlakonda Amulya, Sakowitz Sara, Oxyzolou Ifigenia, Coaston Troy, Benharash Peyman
Cardiovascular Outcomes Research Laboratories (CORELAB), Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Calif.
JTCVS Open. 2024 Dec 24;24:321-331. doi: 10.1016/j.xjon.2024.11.021. eCollection 2025 Apr.
Although provider-patient racial concordance has been associated with improved outcomes among patients of Black race, it is unclear if increased representation at the institutional level is associated with the same benefits.
Adults undergoing coronary artery bypass grafting and valve operations were tabulated from the 2016-2020 National Inpatient Sample. Black-serving quartiles were generated using the annual proportion of Black patients admitted for all diagnoses. The primary end point was in-hospital mortality with Society of Thoracic Surgeons-defined major complications, postoperative length of stay, and costs as secondary outcomes. Mixed regression models were used to ascertain the association between Black-serving quartile designation and outcomes of interest; an interaction term was used to evaluate the incremental association of race and Black-serving quartiles.
Of an estimated 1,203,120 patients, 7.2% were Black. After adjustment, highest Black-serving quartile hospitals demonstrated higher odds of mortality (adjusted odds ratio, 1.18, 95% CI, 1.06-1.30) and major complications (adjusted odds ratio, 1.19, 95% CI, 1.11-1.28) compared with lowest Black-serving quartile hospitals. Notably, Black patients had significantly higher mortality compared with non-Black patients at highest Black-serving quartile institutions (3.3%, 95% CI, 3.0-3.7 vs 2.6, 95% CI, 2.4-2.8), but not at the lowest (3.1%, 95% CI, 1.8-4.4 vs 2.2, 95% CI, 2.1-2.4). Black patients exhibited a stepwise increase in risk of major complication rates, postoperative length of stay, and costs with higher Black-serving quartiles.
Highest Black-serving quartile hospitals had worse clinical outcomes overall compared with those in the lowest Black-serving quartile. Unfortunately, Black patients had additional increased mortality, complications, postoperative length of stay, and costs at high Black-serving quartile institutions, highlighting the compounding effects of patient and hospital-level racial disparities.
尽管医患种族一致性与黑人患者预后改善相关,但机构层面黑人医护人员比例增加是否具有同样益处尚不清楚。
从2016 - 2020年全国住院患者样本中统计接受冠状动脉搭桥术和瓣膜手术的成年人。根据所有诊断的黑人患者年度比例生成黑人服务四分位数。主要终点是住院死亡率以及胸外科医师协会定义的主要并发症、术后住院时间和费用作为次要结局。使用混合回归模型确定黑人服务四分位数指定与感兴趣结局之间的关联;使用交互项评估种族与黑人服务四分位数的增量关联。
在估计的1203120名患者中,7.2%为黑人。调整后,与黑人服务四分位数最低的医院相比,黑人服务四分位数最高的医院死亡率(调整优势比,1.18,95%置信区间,1.06 - 1.30)和主要并发症(调整优势比,1.19,95%置信区间,1.11 - 1.28)的几率更高。值得注意的是,在黑人服务四分位数最高的机构中,黑人患者的死亡率显著高于非黑人患者(3.3%,95%置信区间,3.0 - 3.7对2.6,95%置信区间,2.4 - 2.8),但在最低四分位数时并非如此(3.1%,95%置信区间,1.8 - 4.4对2.2,95%置信区间,2.1 - 2.4)。随着黑人服务四分位数的升高,黑人患者主要并发症发生率、术后住院时间和费用的风险呈逐步增加。
总体而言,黑人服务四分位数最高的医院与最低的医院相比,临床结局更差。不幸的是,在黑人服务四分位数高的机构中,黑人患者的死亡率、并发症、术后住院时间和费用进一步增加,凸显了患者和医院层面种族差异的复合效应。