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基于全国性中国队列研究的未患临床疾病的老年人中多领域休闲活动与认知储备之间的婚姻状况特异性关联

Marital Status-Specific Associations Between Multidomain Leisure Activities and Cognitive Reserve in Clinically Unimpaired Older Adults: Based on a National Chinese Cohort.

作者信息

Cai Cheng, Wang Junyi, Liu Dan, Liu Jing, Zhou Juan, Liu Xiaochang, Song Dan, Li Shiyue, Cui Yuyang, Nie Qianqian, Hu Feifei, Xie Xinyan, Cheng Guirong, Zeng Yan

机构信息

Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan University of Science and Technology, Wuhan 430065, China.

Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan 430065, China.

出版信息

Brain Sci. 2025 Apr 3;15(4):371. doi: 10.3390/brainsci15040371.

DOI:10.3390/brainsci15040371
PMID:40309859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12025604/
Abstract

It is unclear how marital status moderates the association between multidomain leisure activities and the progression of cognitive decline in community-dwelling older adults. Data from the Chinese Longitudinal Healthy Longevity Survey with up to 10 years of follow-up were used. The study included participants aged ≥65 years without cognitive impairment at baseline. Cognitive function was assessed using the Mini-Mental State Examination (MMSE). Linear mixed-effect models were used to evaluate the modifying effect of marriage on leisure activities (multiple types, frequency, and single type) and cognitive decline. A total of 5286 participants (aged 79.01 ± 9.54 years, 50.0% women, and 61.4% rural residents) were enrolled. The results indicated that marital status moderates the relationship between leisure activities and cognitive decline. In the unmarried group, multi-type and high-frequency leisure activities were more strongly associated with slower cognitive decline. Specific activities such as gardening, reading, performing household chores, and playing cards were found to significantly contribute to cognitive protection exclusively within the unmarried group, with no such effect observed in the married group. Marital status affects the relationship between participation in multiple leisure activities and cognitive decline in cognitively intact elderly people. For unmarried older adults, regular participation in leisure activities may be an effective intervention.

摘要

目前尚不清楚婚姻状况如何调节社区居住的老年人多领域休闲活动与认知衰退进展之间的关联。我们使用了来自中国健康与养老追踪调查的数据,该调查有长达10年的随访。该研究纳入了基线时年龄≥65岁且无认知障碍的参与者。使用简易精神状态检查表(MMSE)评估认知功能。线性混合效应模型用于评估婚姻对休闲活动(多种类型、频率和单一类型)和认知衰退的调节作用。共招募了5286名参与者(年龄79.01±9.54岁,50.0%为女性,61.4%为农村居民)。结果表明,婚姻状况调节了休闲活动与认知衰退之间的关系。在未婚组中,多种类型和高频的休闲活动与较慢的认知衰退更密切相关。发现诸如园艺、阅读、做家务和打牌等特定活动仅在未婚组中对认知保护有显著贡献,而在已婚组中未观察到这种效果。婚姻状况影响认知功能正常的老年人参与多种休闲活动与认知衰退之间的关系。对于未婚老年人,定期参与休闲活动可能是一种有效的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/6afcf4447368/brainsci-15-00371-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/ddfaffb5df84/brainsci-15-00371-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/ea1263a4114c/brainsci-15-00371-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/6afcf4447368/brainsci-15-00371-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/ddfaffb5df84/brainsci-15-00371-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/ea1263a4114c/brainsci-15-00371-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4949/12025604/6afcf4447368/brainsci-15-00371-g003.jpg

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本文引用的文献

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J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11). doi: 10.1093/gerona/glae231.
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