Bertelsmann F W, Heimans J J, Weber E J, van der Veen E A, Schouten J A
J Neurol Neurosurg Psychiatry. 1985 Jul;48(7):686-90. doi: 10.1136/jnnp.48.7.686.
Using two identical thermostimulators which operated on the Peltier principle, thermal cutaneous sensation of the hand and the foot was investigated in 36 normal subjects and in 20 patients with diabetic neuropathy. Using a two-alternative forced-choice testing procedure, thermal discrimination thresholds were determined twice. The values found in normal subjects are comparable with data from the literature. It was confirmed that thermal discrimination of the foot decreased with increasing age. In patients with diabetic neuropathy the increased thresholds for the foot could be correlated with length-dependent degeneration of small nerve fibres.
使用两台基于珀耳帖原理运行的相同热刺激器，对36名正常受试者和20名糖尿病性神经病变患者的手部和足部的热皮肤感觉进行了研究。采用二项必选试验程序，对热辨别阈值进行了两次测定。在正常受试者中发现的值与文献数据相当。已证实足部的热辨别能力随年龄增长而下降。在糖尿病性神经病变患者中，足部阈值的升高与小神经纤维的长度依赖性退变有关。
