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影响体外冲击波碎石术治疗胰管结石效果的危险因素。

The risk factors affecting effect of extracorporeal shock wave lithotripsy for pancreatic duct stones.

作者信息

Abdul Sammad, Jiao Xiaofei, Wu Chunying

机构信息

International Education College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Department of Radiology, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou, Zhejiang, China.

出版信息

BMC Gastroenterol. 2025 May 3;25(1):333. doi: 10.1186/s12876-025-03801-6.

Abstract

OBJECTIVES

This study aimed to investigate the factors affecting effect of extracorporeal shock wave lithotripsy (ESWL) for pancreatic duct stones.

MATERIALS AND METHODS

The data of 160 patients who underwent ESWL for pancreatic duct stones in Department of Gastroenterology, First People's Hospital of Hangzhou, Westlake University School of Medicine, from July 2017 to June 2023, were retrospectively analyzed. The age and sex of the patients were recorded. All patients underwent spiral computed tomography (CT) abdominal plain scan. The placement of the pancreatic duct stent was recorded. The maximum CT value of stones was manually measured. The regions of interest (ROI) was delineated using ITK-SNAP software, and the stone volume was recorded. According to the size of residual stones after lithotripsy, 99 patients were included in the complete lithotripsy group (CL Group) and 61 patients in the incomplete lithotripsy group (ICL Group). SPSS 26.0 software was used for processing and analysis. A P value < 0.05 was considered statistically significant.

RESULTS

The Sex, maximum CT value, and volume of pancreatic duct stones were statistically significant in both groups. Binary logistic regression analysis showed that female sex, maximum CT value, and volume of pancreatic duct stones were independent risk factors affecting incomplete ESWL fragmentation in pancreatic duct stones. ICL group had a higher mean number of treatments and mean number of impacts than CL group.

CONCLUSION

The Sex, maximum CT value, and volume of stones were related to the therapeutic effect of ESWL. Female sex, maximum CT value, and volume of stones were independent risk factors affecting incomplete stone fragmentation.

摘要

目的

本研究旨在探讨影响体外冲击波碎石术(ESWL)治疗胰管结石效果的因素。

材料与方法

回顾性分析2017年7月至2023年6月在西湖大学医学院附属杭州市第一人民医院消化内科接受ESWL治疗胰管结石的160例患者的数据。记录患者的年龄和性别。所有患者均接受腹部螺旋计算机断层扫描(CT)平扫。记录胰管支架的放置情况。手动测量结石的最大CT值。使用ITK-SNAP软件勾勒感兴趣区域(ROI),并记录结石体积。根据碎石术后残余结石的大小,将99例患者纳入完全碎石组(CL组),61例患者纳入不完全碎石组(ICL组)。采用SPSS 26.0软件进行处理和分析。P值<0.05被认为具有统计学意义。

结果

两组患者的性别、胰管结石的最大CT值和体积差异均有统计学意义。二元逻辑回归分析显示,女性、胰管结石的最大CT值和体积是影响胰管结石ESWL碎石不完全的独立危险因素。ICL组的平均治疗次数和平均冲击次数均高于CL组。

结论

性别、结石最大CT值和结石体积与ESWL的治疗效果有关。女性、结石最大CT值和结石体积是影响结石破碎不完全的独立危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b12b/12049016/866dfabc84ab/12876_2025_3801_Fig1_HTML.jpg

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