Park Sae-Ra, Choi Ji-Yei, Suk Jangmi, Suh Byung-Fhy, Kim Eunjoo
Clinical Research Lab, AMOREPACIFIC R&I Center, Yongin-si, Gyeonggi-do, Republic of Korea.
Global Medical Research Center, Seocho-gu, Seoul, Republic of Korea.
Skin Res Technol. 2025 Feb-May;31(2-5):e70162. doi: 10.1111/srt.70162.
Dermatological procedures improve skin changes caused by aging. However, few studies have focused on the effect of improving various skin characteristics compared with the concurrent use of cosmetics. We aimed to confirm changes in skin characteristics owing to anti-aging dermatological procedures in the short- and long-term and to determine the efficacy of the procedure when products with anti-aging and repair effects are used together.
We included 42 women (mean age, 47.667 ± 3.183 years) divided into a test (n = 21) and control (n = 21) group, with no history of dermatological procedures within 3 months of the test participation date. The dermatological procedure involved a single application of Thermage treatments, and products containing repair and anti-aging ingredients were used for the test group. The skin changes were assessed using device-based measurements and image analysis up to 4 weeks post-procedure.
Post-procedure side effects were alleviated 1 day after the procedure, and transepidermal water loss (TEWL) improved when the products were used together. Skin hydration, elasticity, density, fine lines, texture, and pores improved at 4 weeks after the procedure. When the test product was also used, the improvement was significantly greater, and TEWL of the face improved in the test group only. Aging-related skin characteristics were improved by Thermage, and the combined use of test products and procedures with repair and anti-aging effects improved skin characteristics.
Dermatological procedures and cosmetic products have internal and external anti-aging effects on the skin, respectively, resulting in synergy.
皮肤科手术可改善因衰老引起的皮肤变化。然而，与同时使用化妆品相比，很少有研究关注改善各种皮肤特征的效果。我们旨在确认抗衰老皮肤科手术在短期和长期内对皮肤特征的改变，并确定在同时使用具有抗衰老和修复作用的产品时该手术的疗效。
我们纳入了42名女性（平均年龄47.667 ± 3.183岁），分为试验组（n = 21）和对照组（n = 21），在试验参与日期前3个月内无皮肤科手术史。皮肤科手术包括单次应用热玛吉治疗，试验组使用含有修复和抗衰老成分的产品。在手术后长达4周的时间内，使用基于设备的测量和图像分析来评估皮肤变化。
术后1天副作用得到缓解，同时使用产品时经表皮水分流失（TEWL）有所改善。术后4周皮肤水合作用、弹性、密度、细纹、质地和毛孔均得到改善。当也使用试验产品时，改善更为显著，且仅试验组面部的TEWL有所改善。热玛吉改善了与衰老相关的皮肤特征，试验产品与具有修复和抗衰老作用的手术联合使用改善了皮肤特征。
皮肤科手术和化妆品分别对皮肤具有内在和外在的抗衰老作用，从而产生协同效应。
