Aung Phyo Zaw, Nararatwanchai Thamthiwat
Department of Dermatology, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.
Obstet Med. 2025 Jun;18(2):127-129. doi: 10.1177/1753495X231214820. Epub 2023 Nov 14.
A 32-year-old Thai woman in her first pregnancy presented with multiple hyperpigmented, hyperkeratotic, pruritic, discrete papules coalescing to form plaques with a rippled pattern on the extensor surfaces of upper and lower limbs, back, chest, and abdomen. Her mother had a similar history. Histopathology of the lesion revealed a diagnosis of lichen amyloidosis, confirmed by the Congo red stain. The lesions had started one year prior and had remained stable before pregnancy; however, they became widespread after pregnancy. Thus, prompting the question as to whether this was a coincidence or if the pregnancy had exacerbated the condition. In this case report, we will discuss our approach to this patient and our opinions concerning the relationship between pregnancy and lichen amyloidosis.
一名32岁首次怀孕的泰国女性，其上肢、下肢、背部、胸部和腹部的伸侧出现多个色素沉着、角化过度、瘙痒的离散丘疹，融合形成具有波纹状图案的斑块。她的母亲有类似病史。病变的组织病理学检查显示诊断为苔藓样淀粉样变，刚果红染色证实。病变始于一年前，在怀孕前一直稳定；然而，怀孕后病变广泛扩散。因此，引发了一个问题，即这是巧合还是怀孕使病情加重。在本病例报告中，我们将讨论我们对该患者的治疗方法以及我们对怀孕与苔藓样淀粉样变之间关系的看法。
