Loomans-Kropp Holli A, Elsaid Mohamed I, Yi Jingbo, Kweon Yesung, Paskett Electra D
Division of Cancer Prevention and Control, Department of Internal Medicine, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America.
PLoS One. 2025 May 5;20(5):e0320792. doi: 10.1371/journal.pone.0320792. eCollection 2025.
To examine the association between the presence of preexisting health conditions (PEC) and the perceived risk of catching COVID-19 at the beginning of the pandemic and assess how risk perceptions changed over time.
We used data collected as part of the "Impact of COVID-19" baseline and follow-up surveys to complete our analyses. Participants were interviewed to collect their perceptions of the risk of catching COVID-19 (baseline and follow-up) and the number and type of PEC. Kruskal-Wallis and chi-square tests were used to assess differences in baseline characteristics, and prevalence ratios were estimated using crude and adjusted modified Poisson generalized linear models.
Of the overall study population, 7,069 participants were eligible for the analysis. The majority (83.7%) of the eligible study population had a history of any PEC. Those with a history of any PEC had a median age of 58 (range: 19-97), were primarily female (67.6%), White non-Hispanic (87.8%), had some college (30.3%), were married or living as married (74.4%), lived in an urban region (67.6%), and reported good (35.4%) or very good (33.9%) health. At baseline, study participants with a history of any PEC were more likely to be concerned about catching COVID-19, using a scale of 0-100, compared to those without PECs (Mean[SD] 60.8[29.8] vs. 53.2[29.7]; p < 0.001), as well as more likely concerned about someone they knew catching COVID-19 (Mean[SD] 70.0[28.8] vs. 64.4[29.4]; p < 0.001). The main effects models showed that self-concern of getting COVID-19 was higher in individuals with any PEC, compared to those with no history of PEC (Prevalence Ratio [PR], 1.15; 95%CI, 1.03-1.29); self-concern was lower at follow-up for those with any PEC, compared to baseline (PR, 0.68; 95%CI, 0.65-0.71). There was evidence of an interaction in the models of concern for self and others, suggesting that one's perception of risk was influenced by both the presence/absence of PECs and study time points.
Individuals with PECs perceived a higher risk of COVID-19 infection for themselves and others towards the beginning of the pandemic, although this perception of susceptibility, or risk, was lower at follow-up. In this study, we showed that attitudes toward health and risk of disease of oneself and others may change throughout a pandemic.
研究大流行初期既往健康状况(PEC)的存在与感染新冠病毒的感知风险之间的关联,并评估风险认知如何随时间变化。
我们使用作为“新冠疫情影响”基线和随访调查一部分收集的数据来完成分析。对参与者进行访谈,以收集他们对感染新冠病毒风险(基线和随访)的认知以及PEC的数量和类型。使用Kruskal-Wallis检验和卡方检验评估基线特征的差异,并使用粗调和调整后的修正泊松广义线性模型估计患病率比。
在整个研究人群中,7069名参与者符合分析条件。大多数(83.7%)符合条件的研究人群有任何PEC病史。有任何PEC病史的人中位年龄为58岁(范围:19 - 97岁),主要为女性(67.6%),非西班牙裔白人(87.8%),上过一些大学(30.3%),已婚或同居(74.4%),居住在城市地区(67.6%),并报告健康状况良好(35.4%)或非常好(33.9%)。在基线时,与没有PEC的参与者相比,有任何PEC病史的研究参与者更有可能担心感染新冠病毒(采用0 - 100分制)(均值[标准差]60.8[29.8]对53.2[29.7];p < 0.001),也更有可能担心他们认识的人感染新冠病毒(均值[标准差]70.0[28.8]对64.4[29.4];p < 0.001)。主要效应模型显示,与没有PEC病史的个体相比,有任何PEC的个体对感染新冠病毒的自我担忧更高(患病率比[PR],1.15;95%置信区间,1.03 - 1.29);与基线相比,有任何PEC的个体在随访时自我担忧较低(PR,0.68;95%置信区间,0.65 - 0.71)。在对自己和他人的担忧模型中有交互作用的证据,表明一个人的风险认知受PEC的有无和研究时间点的影响。
在大流行初期,有PEC的个体认为自己和他人感染新冠病毒的风险更高,尽管这种易感性或风险的认知在随访时较低。在本研究中,我们表明在整个大流行期间,对自身和他人健康及疾病风险的态度可能会发生变化。