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新冠疫情后成人免疫接种的全球状况

Global Status of Adult Immunization Post COVID-19 Pandemic.

作者信息

Vilajeliu Alba, Vega Victor, Gibson Randie, Nogareda Francisco, Wang Xiaojun, Brooks Donald J, Wiysonge Charles Shey, Cakmak Osman Niyazi, Mere Osama, Marti Melanie, Lambach Phillip, Shendale Stephanie, Contreras Marcela, Njambe Emmanuel, Sparrow Erin Grace, Hombach Joachim, Lindstrand Ann

机构信息

Department of Immunization, Vaccines and Biologicals (IVB), World Health Organization, 1211 Geneva, Switzerland.

Special Program Comprehensive Immunization, Pan American Health Organization (PAHO)/World Health Organization Regional Office for the Americas, Washington, DC 20037, USA.

出版信息

Vaccines (Basel). 2025 Apr 11;13(4):401. doi: 10.3390/vaccines13040401.

Abstract

BACKGROUND/OBJECTIVE: Historically, immunization programs have focused on infants, children, and women of reproductive age. COVID-19 vaccination prompted countries to vaccinate adults. The objective of this manuscript is to provide a global overview of adult immunization policies post COVID-19 pandemic.

METHODS

We summarized WHO Strategic Advisory Group of Experts on Immunization (SAGE) recommendations by adult group and analyzed the data reported in 2024 (2023) by WHO Member States (MS) via the WHO/UNICEF electronic Joint Reporting Form on Immunization (eJRF) on national immunization schedules, and from other sources by WHO region and income group.

RESULTS

WHO policy recommendations exist for most of the licensed vaccines targeting adults; however, the inclusion in national immunization schedules is higher in high-income (HICs) and middle-income (MICs) countries. For pregnant women, 90% of MS reported vaccination against COVID-19 (65% in low-income countries [LICs]), 63% against tetanus-containing vaccines (73% in LICs), 57% against influenza (4% in LICs), and 21% against pertussis-containing vaccines (all MICs and HICs). For health workers, 91% against COVID-19 (92% in LICs), 59% against influenza (4% in LICs), and 25% against hepatitis B (10% in LICs). For adults with chronic diseases, COVID-19 vaccination data were not available, 58% against influenza, and 23% against pneumococcal disease. For older adults, more than 90% of MS across all income groups reported COVID-19 vaccination, 59% against influenza (8% of LICs versus 89% of HICs), 17% against pneumococcal, and 7% against herpes zoster (HZ).

CONCLUSION

The disparities in adult immunization policies across income groups highlight the need to improve access and strengthen vaccination efforts. A life course approach is essential to maximize the full potential of immunization across all ages.

摘要

背景/目的:从历史上看,免疫规划主要侧重于婴儿、儿童和育龄妇女。新冠病毒疫苗接种促使各国为成年人接种疫苗。本手稿的目的是提供新冠疫情大流行后成人免疫政策的全球概述。

方法

我们按成人组总结了世界卫生组织免疫战略咨询专家组(SAGE)的建议,并分析了世卫组织成员国(MS)在2024年(2023年)通过世卫组织/联合国儿童基金会免疫电子联合报告表(eJRF)报告的关于国家免疫规划的数据,以及世卫组织按区域和收入组从其他来源获取的数据。

结果

针对大多数已获许可的成人疫苗,世卫组织都有政策建议;然而,高收入国家(HICs)和中等收入国家(MICs)将其纳入国家免疫规划的比例更高。对于孕妇,90%的成员国报告为其接种了新冠病毒疫苗(低收入国家[LICs]为65%),63%接种了含破伤风疫苗(低收入国家为73%),57%接种了流感疫苗(低收入国家为4%),21%接种了含百日咳疫苗(均为中等收入和高收入国家)。对于卫生工作者,91%接种了新冠病毒疫苗(低收入国家为92%),59%接种了流感疫苗(低收入国家为4%),25%接种了乙型肝炎疫苗(低收入国家为10%)。对于患有慢性病的成年人,没有新冠病毒疫苗接种数据,58%接种了流感疫苗,23%接种了肺炎球菌疾病疫苗。对于老年人,所有收入组中超过90%的成员国报告为其接种了新冠病毒疫苗,59%接种了流感疫苗(低收入国家为8%,高收入国家为89%),17%接种了肺炎球菌疫苗,7%接种了带状疱疹(HZ)疫苗。

结论

不同收入组成人免疫政策的差异凸显了改善可及性和加强疫苗接种工作的必要性。采用全生命周期方法对于充分发挥各年龄段免疫的全部潜力至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2e/12031070/60a07cc275fd/vaccines-13-00401-g001.jpg

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