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揭示一名成年男性前额部无先前汗孔瘤的情况下发生的小汗腺汗孔癌的细胞形态学特征:通过文献综述揭示的罕见病例

Elucidating Cytomorphological Features of Eccrine Porocarcinoma on The Forehead Presenting Without Pre-existing Poroma in an Adult Male: A Rarity Unveiled with a Comprehensive Review of Literature.

作者信息

Malik Shaivy, Singh Mukul, Khan Adil Aziz

机构信息

Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

Indian J Surg Oncol. 2025 Apr;16(2):443-449. doi: 10.1007/s13193-024-02130-6. Epub 2024 Nov 25.

Abstract

Eccrine porocarcinoma (EPC), a rare and aggressive skin adnexal malignancy, presents significant diagnostic and management challenges due to its low incidence and clinical resemblance to other skin lesions. The case report highlights its rarity, propensity for aggressive behavior, and the importance of prompt diagnosis for effective management. A 50-year-old male presented with a rapidly enlarging swelling on his forehead, clinically resembling to any other skin lesion. Fine needle aspiration biopsy (FNAB) revealed atypical basaloid cells suggestive of porocarcinoma, confirmed by histopathological examination and immunohistochemistry. The case emphasized the diverse clinical presentation and the utility of FNAB in early diagnosis. This case underscores the comprehensive understanding of EPC, including its clinical, cytological, histopathological, and immunohistological features. It also emphasizes the key cytological features and its role in early diagnosis.

摘要

小汗腺汗孔癌(EPC)是一种罕见且侵袭性强的皮肤附属器恶性肿瘤,因其发病率低且在临床上与其他皮肤病变相似,在诊断和治疗方面面临重大挑战。该病例报告突出了其罕见性、侵袭性行为倾向以及早期诊断对有效治疗的重要性。一名50岁男性患者前额出现迅速增大的肿物,临床上与其他任何皮肤病变相似。细针穿刺活检(FNAB)显示非典型基底样细胞,提示为汗孔癌,经组织病理学检查和免疫组织化学确诊。该病例强调了其多样的临床表现以及FNAB在早期诊断中的作用。此病例强调了对EPC的全面理解,包括其临床、细胞学、组织病理学和免疫组织学特征。它还强调了关键的细胞学特征及其在早期诊断中的作用。

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本文引用的文献

1
Eccrine Porocarcinoma: A Review of the Literature.小汗腺癌:文献综述
Diagnostics (Basel). 2023 Apr 16;13(8):1431. doi: 10.3390/diagnostics13081431.
2
Diagnosis and Management of Porocarcinoma.汗孔癌的诊断与管理
Cancers (Basel). 2022 Oct 25;14(21):5232. doi: 10.3390/cancers14215232.
7
Cytodiagnosis of Eccrine Porocarcinoma of the Scalp.头皮小汗腺汗孔癌的细胞诊断
Int J Trichology. 2017 Oct-Dec;9(4):184-186. doi: 10.4103/ijt.ijt_27_16.
8
Porocarcinoma; presentation and management, a meta-analysis of 453 cases.汗孔癌;临床表现与治疗,453例病例的荟萃分析。
Ann Med Surg (Lond). 2017 Jun 20;20:74-79. doi: 10.1016/j.amsu.2017.06.027. eCollection 2017 Aug.
9
Porocarcinoma with perineural invasion.伴有神经周围浸润的汗腺癌。
Indian Dermatol Online J. 2015 Mar-Apr;6(2):122-5. doi: 10.4103/2229-5178.153018.

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