Díaz-Barreda María D, Boned-Murillo Ana, Bartolomé-Sesé Isabel, Sopeña-Pinilla María, Orduna-Hospital Elvira, Fernández-Espinosa Guisela, Pinilla Isabel
Department of Ophthalmology, Obispo Polanco Hospital, 44002 Teruel, Spain.
Aragón Health Research Institute (IIS Aragón), 50009 Zaragoza, Spain.
Biomedicines. 2025 Apr 11;13(4):943. doi: 10.3390/biomedicines13040943.
In this study, the objective was to assess the correlation between macular function and peripapillary retinal nerve fiber layer (pRNFL) thickness following successful rhegmatogenous retinal detachment (RRD) surgery, as well as the subsequent recovery of visual acuity. : This was a cross-sectional study including 64 eyes from patients with RRD who underwent successful treatment with 23G pars plana vitrectomy (PPV), endophotocoagulation and sulfur-hexafluoride (SF6) were included and compared to a control group consisting of 136 healthy eyes. A complete ophthalmological examination was performed on all participants, including assessment of macular sensitivity using macular integrity assessment (MAIA) microperimetry and pRNFL thickness using DRI-Triton swept-source (SS)-optical coherence tomography (OCT). : In the RRD group, retinal sensitivity was decreased. The temporal (T) sector of the total retina (TR) protocol was thicker, while the superior (S) and inferior (I) sectors of the pRNFL protocol were thinner. Within the RRD group, positive correlations were observed between the nasal (N), I sectors and total thickness of TR protocol and MAIA inferior outer (IO) sector; the I sector and total thickness of the TR protocol and MAIA inferior inner (II) sector; the I sector of the pRNFL protocol and MAIA IO sector. Negative correlations were shown between the S, T sectors and total thickness of the pRNFL protocol and MAIA central (C) sector; the N sector and total thickness of the pRNFL protocol and MAIA central temporal (CT) sector. : RRD leads to a decrease in pRNFL thickness accompanied by reduced macular sensitivity. These changes may be attributed to factors such as the specific location of the RRD, the distribution pattern of the RNFL and the chosen surgical approach.
在本研究中，目的是评估孔源性视网膜脱离（RRD）手术成功后黄斑功能与视乳头周围视网膜神经纤维层（pRNFL）厚度之间的相关性，以及随后视力的恢复情况。这是一项横断面研究，纳入了64例接受23G玻璃体切除术（PPV）、眼内光凝和六氟化硫（SF6）成功治疗的RRD患者的眼睛，并与由136只健康眼睛组成的对照组进行比较。对所有参与者进行了全面的眼科检查，包括使用黄斑完整性评估（MAIA）微视野计评估黄斑敏感性，以及使用DRI-Triton扫频源（SS）光学相干断层扫描（OCT）测量pRNFL厚度。在RRD组中，视网膜敏感性降低。全视网膜（TR）方案的颞侧（T）象限较厚，而pRNFL方案的上方（S）和下方（I）象限较薄。在RRD组内，观察到TR方案的鼻侧（N）、I象限和总厚度与MAIA下方外侧（IO）象限之间呈正相关；TR方案的I象限和总厚度与MAIA下方内侧（II）象限之间呈正相关；pRNFL方案的I象限与MAIA IO象限之间呈正相关。pRNFL方案的S、T象限和总厚度与MAIA中央（C）象限之间呈负相关；pRNFL方案的N象限和总厚度与MAIA中央颞侧（CT）象限之间呈负相关。RRD导致pRNFL厚度降低，同时黄斑敏感性降低。这些变化可能归因于RRD的特定位置、RNFL的分布模式和所选的手术方法等因素。
