帕金森病中的异动症-高热综合征可能从苍白球腹内侧核脑深部电刺激中获益：一例报告
Dyskinesia-Hyperpyrexia Syndrome in Parkinson's Disease May Benefit from GPi Deep Brain Stimulation: A Case Report.
作者信息
Huang Shi-Shi, Ma Lu-Lu, Sheng Han-Song, Liu Rong-Pei, Zhu Shi-Guo, Xu Shan-Shan, Sheng Mei-Ling, Chen Zhu-Ling, Zhang Nu, Zhang Xiong, Wang Jian-Yong
机构信息
Department of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Department of Neurosurgery, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
出版信息
Tremor Other Hyperkinet Mov (N Y). 2025 May 7;15:20. doi: 10.5334/tohm.912. eCollection 2025.
BACKGROUND
Dyskinesia-hyperpyrexia syndrome (DHS) is a rare but life-threatening complication in Parkinson's disease (PD). Its prevention and treatment are clinical challenges.
CASE REPORT
We herein present a case of a female PD patient who experienced recurrent episodes of DHS and levodopa-induced dyskinesia. The complications were alleviated after bilateral globus pallidus internus (GPi) deep brain stimulation (DBS).
DISCUSSION
Our report provides evidence that GPi DBS may reduce the susceptibility to DHS. More evidences are warranted to validate this hypothesis.
背景
异动症-高热综合征（DHS）是帕金森病（PD）中一种罕见但危及生命的并发症。其预防和治疗是临床面临的挑战。
病例报告
我们在此报告一例女性帕金森病患者，该患者反复出现异动症-高热综合征发作及左旋多巴诱导的异动症。双侧内侧苍白球（GPi）脑深部电刺激（DBS）后，这些并发症得到缓解。
讨论
我们的报告提供了证据表明内侧苍白球脑深部电刺激可能降低异动症-高热综合征的易感性。需要更多证据来验证这一假设。
Zotero 插件