Nel J T
S Afr Med J. 1985 Sep 14;68(6):371-4.
The aim of this study was to evaluate the clinical effects of epidural block for pain relief during labour in an obstetric unit which manages mainly high-risk pregnancies. In the majority of the 62 patients studied only 5 ml of a 0,5% solution of bupivacaine was sufficient for effective pain relief. In 75% of patients total pain relief was obtained. Complications of the procedure were hypotension in 32% of patients and bladder atony needing catheterization in 19%. The mean fall in blood pressure was greater in patients with pre-existing hypertension. The incidence of instrumental delivery was 40%, inadequate bearing-down effort being the indication in 54% of these cases. An abnormal fetal heart rate pattern on cardiotocography developed in 13 of 58 fetuses who were monitored internally, while in 3 cases an abnormal pattern because even more abnormal (in one-third of these cases this followed hypotension in the mother). The only statistically significant change in fetal heart rate patterns on cardiotocography was a decrease in the beat-to-beat variability. Epidural block is a very effective form of pain relief during labour but has potentially serious effects, especially in high-risk pregnancies. Precautions to minimize the risk of complications include the administration of intravenous fluid before the procedure and careful monitoring of the patient and her unborn baby. A cardiotocographic monitor is essential for the latter purpose.
本研究的目的是评估在一个主要处理高危妊娠的产科单位中,硬膜外阻滞用于分娩镇痛的临床效果。在研究的62例患者中,大多数仅5毫升0.5%布比卡因溶液就足以有效缓解疼痛。75%的患者实现了完全镇痛。该操作的并发症包括32%的患者出现低血压,19%的患者出现膀胱无张力需要导尿。既往有高血压的患者血压平均下降幅度更大。器械助产率为40%,其中54%的病例因屏气用力不足而进行器械助产。在58例接受宫内监测的胎儿中,13例出现了异常的胎心监护图形,而在3例中,异常图形变得更加异常(其中三分之一的病例是在母亲出现低血压之后)。胎心监护图形上唯一有统计学意义的变化是逐搏变异性降低。硬膜外阻滞是分娩时一种非常有效的镇痛方式,但有潜在的严重影响,尤其是在高危妊娠中。将并发症风险降至最低的预防措施包括在操作前输注静脉液体以及仔细监测患者及其未出生的婴儿。为此目的,胎心监护仪必不可少。