O'Reilly Peter, Loiselle Genevieve, Darragh Ryan, Slipski Carmine, Bay Denice C
Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.
NPJ Antimicrob Resist. 2025 May 13;3(1):39. doi: 10.1038/s44259-025-00108-0.
Decreased bacterial susceptibility to biocides raises concerns due to their influences on antibiotic resistance. The lack of standardized breakpoints, established methods, and consistent terminology complicates this research. This review summarizes techniques for studying biocide resistance mechanisms, susceptibility testing, and in-vitro adaptation methods, highlighting their benefits and limitations. Here, the challenges in studying biocide susceptibility and the need for standardized approaches in biocide research are emphasized for commonly studied biocide classes.
细菌对杀菌剂的敏感性降低因其对抗生素耐药性的影响而引发关注。缺乏标准化的断点、既定方法和一致的术语使这项研究变得复杂。本综述总结了研究杀菌剂耐药机制、药敏试验和体外适应方法的技术，强调了它们的优点和局限性。在此，针对常见的杀菌剂类别，强调了研究杀菌剂敏感性方面的挑战以及杀菌剂研究中采用标准化方法的必要性。
