Kheirollahi Asma, Hamidi Hediyeh, Vatannejad Akram
Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
BMC Res Notes. 2025 May 13;18(1):215. doi: 10.1186/s13104-025-07202-6.
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by diverse clinical and metabolic manifestations. This study aimed to investigate the prevalence of PCOS phenotypes and their association with hematological, biochemical, and hormonal parameters in PCOS, with a particular focus on infertile women and those with recurrent pregnancy loss (RPL).
Phenotype A was the most prevalent phenotype overall and within both infertile and RPL subgroups. However, no significant differences in hematological, biochemical, or hormonal parameters were observed among the PCOS phenotypes, except for lower RBC and hematocrit levels in phenotype F. PCOS women with RPL demonstrate significantly lower levels of RBC, hemoglobin, and hematocrit in phenotype F.
多囊卵巢综合征(PCOS)是一种具有异质性的疾病,其临床和代谢表现多样。本研究旨在调查PCOS表型的患病率及其与PCOS患者血液学、生化和激素参数的关系,特别关注不孕妇女和复发性流产(RPL)患者。
表型A是总体以及不孕和RPL亚组中最常见的表型。然而,除了表型F的红细胞(RBC)和血细胞比容水平较低外,PCOS各表型之间在血液学、生化或激素参数方面未观察到显著差异。患有RPL的PCOS女性在表型F中显示出显著较低的RBC、血红蛋白和血细胞比容水平。