Ulloa-Gutierrez Rolando, Hozbor Daniela, Avila-Aguero María L, Echániz-Aviles Gabriela, Gentile Angela, Torres Torretti Juan Pablo, Heininger Ulrich, Muloiwa Rudzani, Wirsing von König Carl Heinz, Forsyth Kevin, Tan Tina Q
Servicio de Aislamiento, Hospital Nacional de Niños Dr Carlos Sáenz Herrera, Caja Costarricense de Seguro Social, San José, Costa Rica.
Cátedra de Padriatria, Universidad de Ciencias Médicas, San José, Costa Rica.
Open Forum Infect Dis. 2025 May 13;12(5):ofaf154. doi: 10.1093/ofid/ofaf154. eCollection 2025 May.
In 2023, the Global Pertussis Initiative met to assess the burden of and vaccination policies against pertussis in 10 Latin American countries. Although pertussis is a notifiable disease in the represented countries, poor disease awareness, underrecognition in older individuals, and limited laboratory capacity and supplies challenge the collection of robust epidemiological data. Infants in all 10 countries receive a 3-dose primary series followed by ≥2 boosters. Except for Paraguay and Venezuela, governments of the represented countries advise or mandate vaccination in pregnancy; however, coverage rates remain suboptimal. Healthcare providers and the public should be educated on how mothers and other contacts can serve as asymptomatic carriers of (transmitting disease to vulnerable infants) and of the potentially unique presentation of pertussis in adolescents and adults. The burden of pertussis in Latin America can be reduced by improving vaccination coverage of the primary series, increasing vaccination in pregnancy, and instituting universal vaccination of adults.
2023年,全球百日咳倡议组织召开会议,评估了10个拉丁美洲国家百日咳的负担以及针对百日咳的疫苗接种政策。尽管在所代表的国家中,百日咳是一种应报告的疾病,但疾病认知度低、老年个体未被充分识别,以及实验室能力和物资有限,对收集可靠的流行病学数据构成了挑战。所有10个国家的婴儿都接受3剂基础免疫系列接种,随后接种≥2剂加强疫苗。除巴拉圭和委内瑞拉外,所代表国家的政府建议或强制在孕期接种疫苗;然而,接种率仍然不理想。应向医疗保健提供者和公众开展教育,告知母亲和其他接触者如何成为无症状携带者(将疾病传播给易感染的婴儿),以及青少年和成人百日咳可能具有的独特表现。通过提高基础免疫系列的疫苗接种覆盖率、增加孕期接种以及实施成人普遍接种,可以减轻拉丁美洲的百日咳负担。