Dardouri Samia
Department of Computer Science, College of Computing and Information Technology, Shaqra University, Shaqraa, Saudi Arabia.
Front Artif Intell. 2025 Apr 29;8:1563016. doi: 10.3389/frai.2025.1563016. eCollection 2025.
Alzheimer's disease (AD) is a progressive, incurable neurological disorder that leads to a gradual decline in cognitive abilities. Early detection is vital for alleviating symptoms and improving patient quality of life. With a shortage of medical experts, automated diagnostic systems are increasingly crucial in healthcare, reducing the burden on providers and enhancing diagnostic accuracy. AD remains a global health challenge, requiring effective early detection strategies to prevent its progression and facilitate timely intervention. In this study, a deep convolutional neural network (CNN) architecture is proposed for AD classification. The model, consisting of 6,026,324 parameters, uses three distinct convolutional branches with varying lengths and kernel sizes to improve feature extraction. The OASIS dataset used includes 80,000 MRI images sourced from Kaggle, categorized into four classes: non-demented (67,200 images), very mild demented (13,700 images), mild demented (5,200 images), and moderate demented (488 images). To address the dataset imbalance, a data augmentation technique was applied. The proposed model achieved a remarkable 99.68% accuracy in distinguishing between the four stages of Alzheimer's: Non-Dementia, Very Mild Dementia, Mild Dementia, and Moderate Dementia. This high accuracy highlights the model's potential for real-time analysis and early diagnosis of AD, offering a promising tool for healthcare professionals.
阿尔茨海默病(AD)是一种进行性、无法治愈的神经疾病,会导致认知能力逐渐下降。早期检测对于缓解症状和提高患者生活质量至关重要。由于医学专家短缺,自动化诊断系统在医疗保健中变得越来越关键,可减轻医疗人员的负担并提高诊断准确性。AD仍然是一项全球性的健康挑战,需要有效的早期检测策略来防止其进展并促进及时干预。在本研究中,提出了一种用于AD分类的深度卷积神经网络(CNN)架构。该模型由6,026,324个参数组成,使用三个不同长度和内核大小的卷积分支来改进特征提取。所使用的OASIS数据集包括从Kaggle获取的80,000张MRI图像,分为四类:非痴呆(67,200张图像)、极轻度痴呆(13,700张图像)、轻度痴呆(5,200张图像)和中度痴呆(488张图像)。为了解决数据集不平衡问题,应用了数据增强技术。所提出的模型在区分阿尔茨海默病的四个阶段:非痴呆、极轻度痴呆、轻度痴呆和中度痴呆方面取得了99.68%的显著准确率。这种高准确率凸显了该模型在AD实时分析和早期诊断方面的潜力,为医疗保健专业人员提供了一个有前景的工具。