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使用深度学习技术进行阿尔茨海默病的诊断与分类。

Alzheimer's disease diagnosis and classification using deep learning techniques.

作者信息

Al Shehri Waleed

机构信息

Department of Computer Science, College of Computer in Al-Lith, Umm Al-Qura University, Makkah, Saudi Arabia.

出版信息

PeerJ Comput Sci. 2022 Dec 20;8:e1177. doi: 10.7717/peerj-cs.1177. eCollection 2022.

Abstract

Alzheimer's disease is an incurable neurodegenerative disease that affects brain memory mainly in aged people. Alzheimer's disease occurs worldwide and mainly affects people aged older than 65 years. Early diagnosis for accurate detection is needed for this disease. Manual diagnosis by health specialists is error prone and time consuming due to the large number of patients presenting with the disease. Various techniques have been applied to the diagnosis and classification of Alzheimer's disease but there is a need for more accuracy in early diagnosis solutions. The model proposed in this research suggests a deep learning-based solution using DenseNet-169 and ResNet-50 CNN architectures for the diagnosis and classification of Alzheimer's disease. The proposed model classifies Alzheimer's disease into Non-Dementia, Very Mild Dementia, Mild Dementia, and Moderate Dementia. The DenseNet-169 architecture outperformed in the training and testing phases. The training and testing accuracy values for DenseNet-169 are 0.977 and 0.8382, while the accuracy values for ResNet-50 were 0.8870 and 0.8192. The proposed model is usable for real-time analysis and classification of Alzheimer's disease.

摘要

阿尔茨海默病是一种无法治愈的神经退行性疾病,主要影响老年人的大脑记忆。阿尔茨海默病在全球范围内都有发生,主要影响65岁以上的人群。这种疾病需要进行早期诊断以实现准确检测。由于患有该疾病的患者数量众多,健康专家进行人工诊断容易出错且耗时。已经有各种技术应用于阿尔茨海默病的诊断和分类,但早期诊断解决方案仍需要更高的准确性。本研究提出的模型建议使用基于深度学习的解决方案,采用DenseNet-169和ResNet-50卷积神经网络(CNN)架构来诊断和分类阿尔茨海默病。所提出的模型将阿尔茨海默病分为非痴呆、极轻度痴呆、轻度痴呆和中度痴呆。DenseNet-169架构在训练和测试阶段表现更优。DenseNet-169的训练和测试准确率分别为0.977和0.8382,而ResNet-50的准确率分别为0.8870和0.8192。所提出的模型可用于阿尔茨海默病的实时分析和分类。

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