Reka S, Praba T Suriya, Prasanna Mukesh, Reddy Vanipenta Naga Nithin, Amirtharajan Rengarajan
School of Computing, SASTRA Deemed University, Thirumalaisamudram, Thanjavur, 613401, India.
School of Electrical and Electronics Engineering, SASTRA Deemed University, Thirumalaisamudram, Thanjavur, 613401, India.
Sci Rep. 2025 May 15;15(1):16832. doi: 10.1038/s41598-025-01744-2.
PCOS (Poly-Cystic Ovary Syndrome) is a multifaceted disorder that often affects the ovarian morphology of women of their reproductive age, resulting in the development of numerous cysts on the ovaries. Ultrasound imaging typically diagnoses PCOS, which helps clinicians assess the size, shape, and existence of cysts in the ovaries. Nevertheless, manual ultrasound image analysis is often challenging and time-consuming, resulting in inter-observer variability. To effectively treat PCOS and prevent its long-term effects, prompt and accurate diagnosis is crucial. In such cases, a prediction model based on deep learning can help physicians by streamlining the diagnosis procedure, reducing time and potential errors. This article proposes a novel integrated approach, QEI-SAM (Quality Enhanced Image - Segment Anything Model), for enhancing image quality and ovarian cyst segmentation for accurate prediction. GAN (Generative Adversarial Networks) and CNN (Convolutional Neural Networks) are the most recent cutting-edge innovations that have supported the system in attaining the expected result. The proposed QEI-SAM model used Enhanced Super Resolution Generative Adversarial Networks (ESRGAN) for image enhancement to increase the resolution, sharpening the edges and restoring the finer structure of the ultrasound ovary images and achieved a better SSIM of 0.938, PSNR value of 38.60 and LPIPS value of 0.0859. Then, it incorporates the Segment Anything Model (SAM) to segment ovarian cysts and achieve the highest Dice coefficient of 0.9501 and IoU score of 0.9050. Furthermore, Convolutional Neural Network - ResNet 50, ResNet 101, VGG 16, VGG 19, AlexNet and Inception v3 have been implemented to diagnose PCOS promptly. Finally, VGG 19 has achieved the highest accuracy of 99.31%.
多囊卵巢综合征(PCOS)是一种多方面的病症,常影响育龄女性的卵巢形态,导致卵巢上出现大量囊肿。超声成像通常用于诊断PCOS,这有助于临床医生评估卵巢中囊肿的大小、形状和存在情况。然而,手动超声图像分析往往具有挑战性且耗时,会导致观察者之间的差异。为了有效治疗PCOS并预防其长期影响,及时准确的诊断至关重要。在这种情况下,基于深度学习的预测模型可以通过简化诊断程序、减少时间和潜在误差来帮助医生。本文提出了一种新颖的集成方法,即QEI-SAM(质量增强图像 - 分割一切模型),用于提高图像质量和卵巢囊肿分割以进行准确预测。生成对抗网络(GAN)和卷积神经网络(CNN)是最新的前沿创新技术,它们支持该系统获得预期结果。所提出的QEI-SAM模型使用增强超分辨率生成对抗网络(ESRGAN)进行图像增强,以提高分辨率、锐化边缘并恢复超声卵巢图像的精细结构,实现了更好的结构相似性指数(SSIM)为0.938、峰值信噪比(PSNR)值为38.60以及感知相似性损失(LPIPS)值为0.0859。然后,它结合分割一切模型(SAM)来分割卵巢囊肿,实现了最高Dice系数为0.9501和交并比(IoU)分数为0.9050。此外,还实现了卷积神经网络 - ResNet 50、ResNet 101、VGG 16、VGG 19、AlexNet和Inception v3来快速诊断PCOS。最后,VGG 19达到了最高准确率99.31%。