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加拿大社区治疗令有效性研究:定量数据的最新系统综述:加拿大关于社区治疗令有效性的研究:定量数据系统综述的更新

Canadian Studies on the Effectiveness of Community Treatment Orders: An Updated Systematic Review of Quantitative Data: Études canadiennes sur l'efficacité des ordonnances de traitement en milieu communautaire : mise à jour d'un examen systématique des données quantitatives.

作者信息

Kisely Steve, Trott Mike, Iyer Ravi

机构信息

Departments of Psychiatry, Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.

School of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

出版信息

Can J Psychiatry. 2025 May 15:7067437251339215. doi: 10.1177/07067437251339215.

DOI:10.1177/07067437251339215
PMID:40370101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12081430/
Abstract

ObjectivesCommunity treatment orders (CTOs) for people with severe mental illnesses are used across most of Canada. Our previous systematic review of 10 years ago found that the evidence-base was limited to small studies, with only one including controls. This review updates the evidence using studies conducted in Canada over the last decade.MethodsA systematic search of PubMed/Medline, Embase, CINAHL, and PsycINFO for any Canadian study of outcomes following CTO placement from March 2015 to January 2025.ResultsWe identified four articles from three studies. Adding these studies to the previous search gave a total of nine articles from seven studies. None could be included in a meta-analysis. There were reductions in readmission rates and bed-days following CTO placement, while psychiatric symptom, outpatient attendance, treatment adherence participation in psychiatric services and housing all improved. In one study, perceived coercion was no greater in the CTO cases than the controls and being on an order preferable to being in hospital. However, many of the studies were small and only two included controls, of which solely one adjusted for potential confounders using either matching or adjusted analyses. The certainty of evidence was therefore rated as very low.ConclusionsThe evidence-base for the use of CTOs in Canada remains limited. This research gap contrasts with other countries that have conducted large studies using randomized or matched controls and adjusted analyses. There is a need for larger studies with more standardized reporting methods to allow for the pooling of results.Protocol Registration NumberProspectively registered with PROSPERO registration number CRD42024615480.

摘要

目标

加拿大大部分地区都对患有严重精神疾病的人使用社区治疗令(CTO)。我们10年前的系统评价发现,证据基础仅限于小型研究,只有一项研究设有对照组。本评价使用过去十年在加拿大开展的研究更新了相关证据。

方法

对PubMed/Medline、Embase、CINAHL和PsycINFO进行系统检索,查找2015年3月至2025年1月期间加拿大任何关于下达社区治疗令后结局的研究。

结果

我们从三项研究中识别出四篇文章。将这些研究纳入之前的检索后,共有来自七项研究的九篇文章。没有一项研究可纳入荟萃分析。下达社区治疗令后再入院率和住院天数有所降低,同时精神症状、门诊就诊率、治疗依从性、参与精神科服务情况和住房状况均有所改善。在一项研究中,社区治疗令组患者感受到的强制程度并不高于对照组,而且接受社区治疗令比住院更可取。然而,许多研究规模较小,只有两项研究设有对照组,其中仅有一项研究使用匹配或校正分析对潜在混杂因素进行了校正。因此,证据的确定性被评为非常低。

结论

加拿大使用社区治疗令的证据基础仍然有限。这一研究差距与其他国家形成对比,其他国家开展了使用随机或匹配对照以及校正分析的大型研究。需要开展规模更大、报告方法更标准化的研究,以便汇总结果。

方案注册号

前瞻性注册于PROSPERO,注册号为CRD42024615480。

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