Bernstein I L, Treneer C M, Kott J N
Am J Physiol. 1985 Sep;249(3 Pt 2):R296-300. doi: 10.1152/ajpregu.1985.249.3.R296.
Growth of a Leydig cell [LTW (m)] tumor in rats is associated with the development of significant hypophagia and severe aversions to the available diet. Lesions of the area postrema and nearby caudal medial area of the solitary tract were found to block or greatly attenuate the anorexia and food aversions that typically accompany the growth of this tumor. Thus these tumor-induced symptoms may be associated with the detection of blood-borne chemicals by cells located in or near the area postrema.
大鼠睾丸间质细胞瘤[LTW（m）]的生长与严重的摄食减少以及对现有饮食的强烈厌恶有关。研究发现，最后区及附近孤束尾内侧区的损伤可阻断或大大减轻该肿瘤生长时通常伴随的厌食和食物厌恶症状。因此，这些肿瘤诱发的症状可能与位于最后区或其附近的细胞对血源化学物质的检测有关。
