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中国南北方1950 - 2021年人间布鲁氏菌病流行病学演变特征及社会经济因素相关性分析

Epidemiological Evolution Profile of Human Brucellosis and Socioeconomic Factor Correlation Analysis - Southern and Northern Areas, China, 1950-2021.

作者信息

Liu Zhiguo, Wang Miao, Shi Yue, Wang Liping, Ren Xiang, Li Zhenjun, Zheng Canjun

机构信息

National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Ulanqab Center for Disease Control and Prevention, Jining City, Inner Mongolia Autonomous Region, China.

出版信息

China CDC Wkly. 2025 Apr 4;7(14):460-466. doi: 10.46234/ccdcw2025.076.

DOI:10.46234/ccdcw2025.076
PMID:40376445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12075453/
Abstract

INTRODUCTION

Human brucellosis poses a serious public health concern in China, however, epidemiological evolution of disease in southern and northern China remains unclear.

METHODS

The number of cases, incidence rate, geographic and temporal distribution, and social factors were analyzed to illustrate the epidemiological change.

RESULTS

About 97.6% of cases consistently located in the northern area are attributed to the tens of thousands of livestock farming. This underscores the need to prioritize strengthening surveillance and control measures in the northern. By contrast, only 2.4% of cases were in the southern area. These data indicate that controlling brucellosis in the northern will help reduce the incidence in the southern. There was an apparent shift from historical multiple-species prevalence to the present dominance of a single species, . Mutton price and production were closely correlated with the number of cases, implying that strains were accompanied by these factors, co-driving the persistent epidemic of brucellosis and expanding from the northern toward the southern.

CONCLUSIONS

The control and prevention of brucellosis in the northern have become extremely complex sociological issues. It is important to draw attention to the worsening epidemic situation and to mobilize the nation's full strength to curb this trend.

摘要

引言

人类布鲁氏菌病在中国构成严重的公共卫生问题,然而,中国南方和北方该疾病的流行病学演变仍不清楚。

方法

分析病例数量、发病率、地理和时间分布以及社会因素,以阐明流行病学变化。

结果

北方地区约97.6%的病例始终归因于数以万计的畜牧业养殖。这突出表明有必要优先加强北方的监测和控制措施。相比之下,南方地区仅有2.4%的病例。这些数据表明,控制北方的布鲁氏菌病将有助于降低南方的发病率。从历史上的多物种流行到目前单一物种占主导地位有明显转变。羊肉价格和产量与病例数量密切相关,这意味着菌株伴随着这些因素,共同推动布鲁氏菌病的持续流行并从北方蔓延至南方。

结论

北方布鲁氏菌病的防控已成为极其复杂的社会学问题。重视疫情恶化情况并动员全国全力遏制这一趋势很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b55a/12075453/4334b62de3da/ccdcw-7-14-460-5.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b55a/12075453/402c7b7d4021/ccdcw-7-14-460-1.jpg
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本文引用的文献

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China CDC Wkly. 2023 Jan 6;5(1):17-22. doi: 10.46234/ccdcw2023.004.
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Brucellosis control methods with an emphasis on vaccination: a systematic review.布鲁氏菌病防控方法研究——以疫苗接种为例:系统综述
Expert Rev Anti Infect Ther. 2022 Jul;20(7):1025-1035. doi: 10.1080/14787210.2022.2066521. Epub 2022 Apr 25.
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Spatiotemporal distribution of human brucellosis in Inner Mongolia, China, in 2010-2015, and influencing factors.
2010-2015 年中国内蒙古人间布鲁氏菌病的时空分布及影响因素。
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Epidemiological Characteristics and Spatiotemporal Trend Analysis of Human Brucellosis in China, 1950-2018.中国布鲁氏菌病的流行特征及时空趋势分析,1950-2018 年。
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