• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

多发性脊柱硬膜外脓肿的罕见表现:一例报告

An uncommon presentation of multiple spinal epidural abscesses: A case report.

作者信息

Karaja Saja, Alassaf Shafiq, Assaf Ahed, Tannous Elias, Alassaad Rima, Alassad Ghiath

机构信息

Faculty of Medicine, Hama University, Hama, Syria.

Faculty of Medicine, Hama University, Hama, Syria.

出版信息

Int J Surg Case Rep. 2025 Jun;131:111435. doi: 10.1016/j.ijscr.2025.111435. Epub 2025 May 13.

DOI:10.1016/j.ijscr.2025.111435
PMID:40378422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12145702/
Abstract

INTRODUCTION

Spinal epidural abscess (SEA) is a rare but severe infection occurring in the epidural space of the spinal cord, increasingly associated with invasive spinal procedures and intravenous drug use. Recognizing and accurately diagnosing SEA is crucial due to its potential neurological impact.

PRESENTATION OF CASE

A 51-year-old male presented with urinary and bowel obstruction, right-sided hemiplegia, fever, and jaundice. Neurological examination revealed pronounced deficits, while imaging and cerebrospinal fluid analysis confirmed multiple epidural abscesses. Cultures identified Staphylococcus aureus sensitive to vancomycin and meropenem.

DISCUSSION

The case underscores the variable presentations and nonspecific symptoms of SEA, highlighting the importance of an accurate medical history and timely imaging for diagnosis. Early intervention with surgical drainage and antibiotic therapy based on culture sensitivity is essential for improving outcomes.

CONCLUSION

This case emphasizes the need for heightened awareness of SEA, particularly in patients with risk factors, to ensure prompt diagnosis and treatment to prevent irreversible neurological damage.

摘要

引言

脊髓硬膜外脓肿(SEA)是一种发生在脊髓硬膜外间隙的罕见但严重的感染,越来越多地与侵入性脊柱手术和静脉药物使用相关。由于其潜在的神经学影响,认识并准确诊断SEA至关重要。

病例介绍

一名51岁男性出现尿路和肠道梗阻、右侧偏瘫、发热和黄疸。神经学检查显示明显缺陷,而影像学和脑脊液分析证实存在多个硬膜外脓肿。培养物鉴定出对万古霉素和美罗培南敏感的金黄色葡萄球菌。

讨论

该病例强调了SEA的表现多样和症状不具特异性,突出了准确病史和及时影像学检查对诊断的重要性。基于培养敏感性进行手术引流和抗生素治疗的早期干预对于改善预后至关重要。

结论

本病例强调需要提高对SEA的认识,特别是对有危险因素的患者,以确保及时诊断和治疗,防止不可逆转的神经损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/2e15427dab94/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/abb038e3fc28/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/28f56b67831e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/053ef9c4aa33/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/dc64b8950e0a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/2e15427dab94/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/abb038e3fc28/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/28f56b67831e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/053ef9c4aa33/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/dc64b8950e0a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133b/12145702/2e15427dab94/gr5.jpg

相似文献

1
An uncommon presentation of multiple spinal epidural abscesses: A case report.多发性脊柱硬膜外脓肿的罕见表现:一例报告
Int J Surg Case Rep. 2025 Jun;131:111435. doi: 10.1016/j.ijscr.2025.111435. Epub 2025 May 13.
2
Spinal Epidural Abscess.脊柱硬膜外脓肿
J Educ Teach Emerg Med. 2020 Jan 15;5(1):S26-S52. doi: 10.21980/J8T938. eCollection 2020 Jan.
3
Vesicoureteral Reflux膀胱输尿管反流
4
Hydromyelia secondary to spinal epidural abscess. A case report.继发于脊髓硬膜外脓肿的脊髓空洞症。一例病例报告。
Neuroradiol J. 2010 Jun;23(3):339-42. doi: 10.1177/197140091002300314. Epub 2010 Jun 30.
5
Spinal epidural abscess: a meta-analysis of 915 patients.脊柱硬膜外脓肿:915例患者的荟萃分析
Neurosurg Rev. 2000 Dec;23(4):175-204; discussion 205. doi: 10.1007/pl00011954.
6
Primary spinal epidural hematoma mimicking stroke: A case report of rare diagnostic challenge.酷似中风的原发性脊髓硬膜外血肿:一例罕见诊断挑战的病例报告
Int J Surg Case Rep. 2025 Feb;127:110932. doi: 10.1016/j.ijscr.2025.110932. Epub 2025 Jan 23.
7
Rare association between spinal epidural abscess and septic arthritis of the hip in pediatric age: Case report.小儿脊髓硬膜外脓肿与髋关节化脓性关节炎之间的罕见关联:病例报告。
Int J Surg Case Rep. 2024 Aug;121:110004. doi: 10.1016/j.ijscr.2024.110004. Epub 2024 Jul 4.
8
Complete Spinal Cord Injury Secondary to Serratia marcescens Spinal Epidural Abscess: A Report of Significant Neurological Improvement After a Delayed Presentation.继发于粘质沙雷氏菌脊柱硬膜外脓肿的完全性脊髓损伤:一例延迟就诊后神经功能显著改善的报告
Cureus. 2023 Aug 31;15(8):e44451. doi: 10.7759/cureus.44451. eCollection 2023 Aug.
9
Spinal Epidural Abscess: A Single-Center Retrospective Review of Incidence, Risk Factors, and Management at a Community Hospital.脊柱硬膜外脓肿:社区医院发病率、危险因素及治疗的单中心回顾性研究
Cureus. 2025 Apr 21;17(4):e82727. doi: 10.7759/cureus.82727. eCollection 2025 Apr.
10
A Rare Multilevel Spinal Epidural Abscess With Streptococcus agalactiae in an Adult With Uncontrolled Diabetes: A Case Report.一名患有未控制糖尿病的成人罕见的多节段脊柱硬膜外脓肿伴无乳链球菌感染:病例报告
Cureus. 2023 Aug 1;15(8):e42802. doi: 10.7759/cureus.42802. eCollection 2023 Aug.

本文引用的文献

1
Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review.乳腺癌化疗后硬膜外脓肿形成:一例报告及文献复习
Front Surg. 2025 Jan 23;12:1388278. doi: 10.3389/fsurg.2025.1388278. eCollection 2025.
2
Efficacy of Additional Surgical Decompression on Functional Outcome in Pyogenic Spinal Epidural Abscess With No Neurological Deficit.无神经功能缺损的化脓性脊柱硬膜外脓肿附加手术减压对功能结局的疗效
Korean J Neurotrauma. 2024 Dec 27;20(4):276-288. doi: 10.13004/kjnt.2024.20.e48. eCollection 2024 Dec.
3
The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.
SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
4
Epidural abscess formation after chemoradiation therapy for esophageal cancer: A case report and literature review.食管癌放化疗后硬膜外脓肿形成:病例报告及文献复习。
Medicine (Baltimore). 2022 May 27;101(21):e29426. doi: 10.1097/MD.0000000000029426.
5
High risk and low prevalence diseases: Spinal epidural abscess.高危低发疾病:脊柱硬膜外脓肿。
Am J Emerg Med. 2022 Mar;53:168-172. doi: 10.1016/j.ajem.2022.01.008. Epub 2022 Jan 13.
6
Cerebrospinal Fluid (CSF) Analysis and Interpretation in Neurocritical Care for Acute Neurological Conditions.急性神经系统疾病神经重症监护中的脑脊液(CSF)分析与解读
Indian J Crit Care Med. 2019 Jun;23(Suppl 2):S115-S119. doi: 10.5005/jp-journals-10071-23187.
7
The time-sensitive challenge of diagnosing spinal epidural abscess in the emergency department.急诊科诊断脊髓硬膜外脓肿的时间敏感性挑战。
Intern Emerg Med. 2017 Dec;12(8):1179-1183. doi: 10.1007/s11739-017-1718-5. Epub 2017 Aug 4.
8
An institutional series and contemporary review of bacterial spinal epidural abscess: current status and future directions.细菌性脊柱硬膜外脓肿的机构性系列研究及当代综述:现状与未来方向
Neurosurg Focus. 2014 Aug;37(2):E9. doi: 10.3171/2014.6.FOCUS14146.
9
Spinal epidural abscesses: risk factors, medical versus surgical management, a retrospective review of 128 cases.脊髓硬膜外脓肿:危险因素、内科与外科治疗,128 例回顾性研究。
Spine J. 2014 Feb 1;14(2):326-30. doi: 10.1016/j.spinee.2013.10.046. Epub 2013 Nov 12.
10
Management of postoperative spinal infections.术后脊柱感染的管理
World J Orthop. 2012 Nov 18;3(11):182-9. doi: 10.5312/wjo.v3.i11.182.