Matzel W
Arch Geschwulstforsch. 1985;55(4):259-64.
The malignant mesothelioma was proved by autopsy as cause for death in 55 cases--42 men and 13 women. 4 men had the tumor without pleural effusion. Transthoracic fine needle biopsy confirmed the suspicion 3 times. The fluids caused by the tumor were exudates 50 times. One fluid was a transudate. Cytological examinations led to the partition into four sections with the following main findings: histiocytes, mesothelial cells also in clusters, tumor cells--21 cases; tumor cells without perceptibility of the matrix--18 cases; cytological empty sediments--8 cases; finding of inflammation--4 cases. The determination of the level of hyaluronic acid in pleural fluids by a colorimetric test proved a malignant mesothelioma in one third of these cases. The synopsis of the named parameters together with clinical dates in general use gives the possibility to put up the diagnosis of the primarily malignant disease of the pleura during lifetime of a patient.
尸检证实55例（42名男性和13名女性）的死亡原因是恶性间皮瘤。4名男性患有无胸腔积液的肿瘤。经胸细针活检3次证实了怀疑。肿瘤引起的液体50次为渗出液。1次为漏出液。细胞学检查分为四个部分，主要发现如下：组织细胞、成簇的间皮细胞、肿瘤细胞——21例；无法识别基质的肿瘤细胞——18例；细胞学空沉淀物——8例；炎症发现——4例。通过比色试验测定胸腔积液中的透明质酸水平，在三分之一的这些病例中证实为恶性间皮瘤。上述参数与常用临床数据的综合分析，使得在患者生前做出胸膜原发性恶性疾病的诊断成为可能。
