Alzaabi Fatema M, Al Tarawneh Dana J, Al Tarawneh Yusuf J, Khan Abdallah, Khan Mohammed Abdul Muqsit, Siddiqui Tabish W, Siddiqui Raqshan W, Nishat Syed Muhammad Hayyan, Alzaabi Asma A, Siddiqui Shiza W
Internal Medicine, RAK Medical and Health Sciences University, Ras Al Khaimah, ARE.
Internal Medicine, King Khalid University Hospital, Abha, SAU.
Cureus. 2025 Apr 17;17(4):e82413. doi: 10.7759/cureus.82413. eCollection 2025 Apr.
Restless legs syndrome (RLS), also called Willis-Ekbom disease (WED), is a condition marked by an overwhelming urge to move the legs, particularly during rest or at night. Treatments, including intravenous iron, show potential, but further studies are needed to establish their long-term safety and efficacy. The findings integrate various studies to better understand diagnosis, mechanisms, and treatment options for RLS. This review explores the connection between RLS and iron deficiency, emphasizing iron metabolism and its potential role in disease development.
不宁腿综合征（RLS），也称为威利斯-埃克博姆病（WED），是一种以强烈的腿部活动冲动为特征的病症，尤其是在休息时或夜间。包括静脉注射铁剂在内的治疗方法显示出了潜力，但需要进一步研究以确定其长期安全性和有效性。这些发现整合了各项研究，以更好地理解不宁腿综合征的诊断、发病机制和治疗选择。这篇综述探讨了不宁腿综合征与缺铁之间的联系，强调了铁代谢及其在疾病发展中的潜在作用。
