Gozalo Alfonso S, Elkins William R
Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
J Med Primatol. 2025 Jun;54(3):e70024. doi: 10.1111/jmp.70024.
Owl monkeys (Aotus spp.) are the only nocturnal simian primates and, as such, they are very different from other nonhuman primate species. Owl monkeys have been used as animal models in malaria research for over 50 years; however, they are also useful models to study a wide range of infectious and some noninfectious diseases. In addition, owl monkeys are spontaneously affected by a wide range of bacterial, viral, mycotic, and parasitic diseases, some of them with zoonotic potential that need to be considered when using this genus in biomedical research. Here we briefly review the research use and spontaneous diseases of this unique genus.
夜猴（夜猴属）是唯一的夜行性猿猴灵长类动物，因此，它们与其他非人类灵长类物种有很大不同。在疟疾研究中，夜猴作为动物模型已被使用了50多年；然而，它们也是研究多种传染病和一些非传染病的有用模型。此外，夜猴会自发感染多种细菌、病毒、真菌和寄生虫疾病，其中一些具有人畜共患病的潜力，在生物医学研究中使用该属动物时需要加以考虑。在此，我们简要回顾一下这个独特属的研究用途和自发性疾病。
