Phillips S C
Exp Neurol. 1985 Jun;88(3):748-56. doi: 10.1016/0014-4886(85)90085-8.
For 4 months C57 mice were fed a nutritionally complete diet containing 9% alcohol or isocaloric sucrose and killed then or after 4 months recovery on standard food pellets. Electron microscopy was used to count synapses among the cerebellar Purkinje cell dendrites and a significant 13% reduction was found in the alcohol recovery group. The shape of the postsynaptic density material was studied and a significant 11% increase in length found in the alcohol group. The smaller thickness of the postsynaptic material in animals of the alcohol recovery group may be representative of new synaptic formation.
对C57小鼠喂食含9%酒精或等热量蔗糖的营养完全饮食，持续4个月，然后处死，或者在恢复食用标准食丸4个月后处死。使用电子显微镜对小脑浦肯野细胞树突间的突触进行计数，发现酒精恢复组突触数量显著减少了13%。研究了突触后致密物质的形状，发现酒精组的长度显著增加了11%。酒精恢复组动物突触后物质较薄的厚度可能代表新突触的形成。
