Phillips S C, Cragg B G
Exp Neurol. 1983 Apr;80(1):218-26. doi: 10.1016/0014-4886(83)90018-3.
For 4 months C57 black mice were fed a nutritionally complete diet containing 9% alcohol or isocaloric sucrose and killed then or after 4 months recovery on standard food pellets. The number of cells in a thin plastic section of hippocampus was unchanged in field CA1 by alcohol exposure but was reduced 9% during withdrawal from alcohol. Electron microscopy was used to count synapses among the basal dendrites and no significant change was found in any treatment group. The spine heads were measured and found to be smaller in the alcohol group than in the sucrose group; many of the spines (in the alcohol group) were too small to be visible with the light microscope.
对C57黑鼠喂食含9%酒精或等热量蔗糖的营养完全的饮食，持续4个月，然后处死，或者在以标准食丸恢复4个月后处死。海马体薄塑料切片中的细胞数量，在CA1区，酒精暴露未使其改变，但在戒酒期间减少了9%。使用电子显微镜对基底树突之间的突触进行计数，未发现任何治疗组有显著变化。对棘突头部进行测量，发现酒精组的比蔗糖组的小；酒精组的许多棘突太小，在光学显微镜下无法看到。
