Motallebi Afsoon, Karimi Ali, Mazhari Fatemeh, Hoseinzadeh Melika
Department of Pediatric Dentistry, School of Dentistry, North Khorasan University of Medical Sciences, Bojnourd, Iran.
Dentist, Bojnourd, Iran.
Saudi Dent J. 2025 May 19;37(4-6):8. doi: 10.1007/s44445-025-00012-3.
The present randomized clinical trial with a split-mouth design investigated the effectiveness of 30% silver diamine fluoride (SDF) compared to 5% sodium flouride varnish (NaD) in arresting proximal caries in the primary molars of preschool-aged children. Forty-three children with contralateral initial proximal carious lesions on primary molars were included. Caries status at the baseline was recorded using clinical and radiographic indices. Lesions restricted to the enamel or the exterior third of dentin were included. A sufficient space was created between the contacts using elastic separators. Then, 5% NaF varnish and 30% SDF were randomly applied to either side of the mouth. Six months later, bitewing radiographs were obtained, and the post-intervention caries scores were compared with the baseline radiographs. Children's oral hygiene was recorded via a questionnaire. The findings indicated that the baseline and post-intervention caries status were comparable between the groups. The success rate of the SDF treatment (74.4%) and the NaF varnish (67.5%) was comparable. Baseline radiographic caries status was significantly related to the treatment result in the NaF group (p = 0.047). Dental flossing was significantly associated with the treatment result when SDF was used (p = 0.027). In conclusion, both fluoride-containing materials exhibited comparable efficacy in arresting early proximal caries lesions in primary molars. SDF 30% showed a higher but insignificant success rate in arresting initial proximal lesions of the primary molar compared to NaF 5% varnish.Trial registration: IRCT, IRCT20220425054647N1. Registered on 24 September 2022, https://en.irct.ir/trial/63168 .
本项采用双侧对照设计的随机临床试验，研究了30%氟化银胺（SDF）与5%氟化钠 varnish（NaD）相比，在预防学龄前儿童乳磨牙邻面龋方面的有效性。纳入了43名双侧乳磨牙有初始邻面龋损的儿童。使用临床和影像学指标记录基线时的龋病状况。纳入仅限于牙釉质或牙本质外层三分之一的病变。使用弹性分离器在接触点之间创造足够的空间。然后，将5% NaF varnish和30% SDF随机涂于口腔两侧。6个月后，拍摄咬合翼片，并将干预后的龋病评分与基线X线片进行比较。通过问卷记录儿童的口腔卫生情况。结果表明，两组之间基线和干预后的龋病状况具有可比性。SDF治疗组（74.4%）和NaF varnish组（67.5%）的成功率相当。基线影像学龋病状况与NaF组的治疗结果显著相关（p = 0.047）。使用SDF时，牙线使用情况与治疗结果显著相关（p = 0.027）。总之，两种含氟材料在预防乳磨牙早期邻面龋损方面表现出相当的疗效。与5% NaF varnish相比，30% SDF在预防乳磨牙初始邻面龋损方面成功率更高，但差异不显著。试验注册：IRCT，IRCT20220425054647N1。于2022年9月24日注册，https://en.irct.ir/trial/63168 。
