Pastor-Vargas Rafael, Antón-Munárriz Cristina, Haut Juan M, Robles-Gómez Antonio, Paoletti Mercedes E, Benítez-Andrades José Alberto
Communications and Control Systems, Computer Engineering Science Faculty, UNED, Calle Juan del Rosal 16, 28040 Madrid, Spain.
Radiology area, Hospital Universitario de Navarra, Navarra, Spain.
Health Inf Sci Syst. 2025 May 20;13(1):36. doi: 10.1007/s13755-025-00352-8. eCollection 2025 Dec.
Cerebrovascular accident (CVA), commonly known as stroke, stands as a significant contributor to contemporary mortality and morbidity rates, often leading to lasting disabilities. Early identification is crucial in mitigating its impact and reducing mortality. Non-contrast computed tomography (NCCT) remains the primary diagnostic tool in stroke emergencies due to its speed, accessibility, and cost-effectiveness. NCCT enables the exclusion of hemorrhage and directs attention to ischemic causes resulting from arterial flow obstruction. Quantification of NCCT findings employs the Alberta Stroke Program Early Computed Tomography Score (ASPECTS), which evaluates affected brain structures. This study seeks to identify early alterations in NCCT density in patients with stroke symptoms using a binary classifier distinguishing NCCT scans with and without stroke. To achieve this, various well-known deep learning architectures, namely VGG3D, ResNet3D, and DenseNet3D, validated in the ImageNet challenges, are implemented with 3D images covering the entire brain volume. The training results of these networks are presented, wherein diverse parameters are examined for optimal performance. The DenseNet3D network emerges as the most effective model, attaining a training set accuracy of 98% and a test set accuracy of 95%. The aim is to alert medical professionals to potential stroke cases in their early stages based on NCCT findings displaying altered density patterns.
脑血管意外(CVA),通常称为中风,是导致当代死亡率和发病率的重要因素,常常导致永久性残疾。早期识别对于减轻其影响和降低死亡率至关重要。非增强计算机断层扫描(NCCT)因其速度、可及性和成本效益,仍然是中风急症的主要诊断工具。NCCT能够排除出血情况,并将注意力指向由动脉血流阻塞导致的缺血原因。NCCT结果的量化采用阿尔伯塔卒中项目早期计算机断层扫描评分(ASPECTS),该评分用于评估受影响的脑结构。本研究旨在使用二元分类器区分有或无中风的NCCT扫描,以识别有中风症状患者的NCCT密度早期变化。为实现这一目标,在ImageNet挑战赛中得到验证的各种著名深度学习架构,即VGG3D、ResNet3D和DenseNet3D,被应用于覆盖整个脑容积的3D图像。展示了这些网络的训练结果,其中对各种参数进行了检查以获得最佳性能。DenseNet3D网络成为最有效的模型,训练集准确率达到98%,测试集准确率达到95%。目的是根据显示密度模式改变的NCCT结果,提醒医疗专业人员注意潜在的早期中风病例。