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心房黏液瘤与风湿性二尖瓣狭窄:术前数天发生栓塞性中风

Atrial Myxoma and Rheumatic Mitral Stenosis: Embolic Stroke Strikes Days Before Surgery.

作者信息

Jamal Tayyebah, Hashmi Abdullah, Hashmi Hafsa, Hashmi Kashif A, Akhtar Ammar, Khattak Muhammad S

机构信息

Cardiology, Nishtar Medical University, Multan, PAK.

Medicine, Quaid-e-Azam Medical College, Bahawalpur, PAK.

出版信息

Cureus. 2025 Apr 21;17(4):e82666. doi: 10.7759/cureus.82666. eCollection 2025 Apr.

DOI:10.7759/cureus.82666
PMID:40400830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12093133/
Abstract

Cardiac myxomas are the most common primary cardiac tumors. Their primary location is the left atrium, but they can arise in any cardiac chamber. Although histologically benign, atrial myxomas are functionally malignant due to their high embolic potential, which can lead to severe complications such as ischemic stroke. Left atrial myxoma can mimic mitral stenosis by causing obstruction to the blood flow at the level of the mitral valve. In developing countries, rheumatic mitral valve is the most common cause of mitral stenosis, and the concurrent occurrence of mitral stenosis and rheumatic heart disease is a rarity. We present a case of a 43-year-old man diagnosed with both conditions who developed an ischemic stroke due to tumor embolization two days prior to planned surgical intervention. This case underscores the importance of timely diagnosis and management in patients with concurrent cardiac pathologies.

摘要

心脏黏液瘤是最常见的原发性心脏肿瘤。其主要部位是左心房,但也可发生于任何心腔。虽然组织学上为良性,但心房黏液瘤因其高栓塞风险而具有功能上的恶性,可导致严重并发症,如缺血性中风。左心房黏液瘤可通过阻塞二尖瓣水平的血流来模拟二尖瓣狭窄。在发展中国家,风湿性二尖瓣是二尖瓣狭窄最常见的病因,二尖瓣狭窄与风湿性心脏病同时发生的情况很少见。我们报告一例43岁男性患者,同时患有这两种疾病,在计划进行手术干预前两天因肿瘤栓塞发生了缺血性中风。该病例强调了对合并心脏疾病患者进行及时诊断和管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/376db4c3a5b7/cureus-0017-00000082666-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/061cf8d09f0a/cureus-0017-00000082666-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/2243ab457210/cureus-0017-00000082666-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/973c6c38b722/cureus-0017-00000082666-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/f8787c93660a/cureus-0017-00000082666-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/376db4c3a5b7/cureus-0017-00000082666-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/061cf8d09f0a/cureus-0017-00000082666-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/2243ab457210/cureus-0017-00000082666-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/973c6c38b722/cureus-0017-00000082666-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/f8787c93660a/cureus-0017-00000082666-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec3/12093133/376db4c3a5b7/cureus-0017-00000082666-i05.jpg

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本文引用的文献

1
Atrial Myxoma: An Unusual Etiology of Ischemic Stroke in an Adult Patient.心房黏液瘤:成年患者缺血性卒中的罕见病因。
Cureus. 2023 Jun 18;15(6):e40599. doi: 10.7759/cureus.40599. eCollection 2023 Jun.
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Giant left atrial myxoma causing acute ischemic stroke.巨大左心房黏液瘤导致急性缺血性脑卒中。
Future Cardiol. 2023 Mar;19(3):149-154. doi: 10.2217/fca-2022-0104. Epub 2023 May 4.
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Recurrent Ischemic Stroke in a Patient with Atrial Myxoma: A Case Report.心房黏液瘤患者复发性脑梗死:1 例报告。
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Cardiac myxomas: A narrative review.心脏黏液瘤:一篇叙述性综述。
World J Cardiol. 2022 Apr 26;14(4):206-219. doi: 10.4330/wjc.v14.i4.206.
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Cardiac myxomas: clinical presentation, diagnosis and management.心脏黏液瘤:临床表现、诊断与治疗
Heart. 2022 May 12;108(11):827-833. doi: 10.1136/heartjnl-2021-319479.
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Atrial Myxoma Mimicking Mitral Stenosis.酷似二尖瓣狭窄的心房黏液瘤
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Perioperative management of adult patients with a history of stroke or transient ischaemic attack undergoing elective non-cardiac surgery.有中风或短暂性脑缺血发作病史的成年患者接受择期非心脏手术的围手术期管理。
Clin Med (Lond). 2016 Dec;16(6):535-540. doi: 10.7861/clinmedicine.16-6-535.
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Rheumatic mitral stenosis in children: more accelerated course in sub-Saharan patients.儿童风湿性二尖瓣狭窄:撒哈拉以南地区患者病情进展更迅速。
BMC Cardiovasc Disord. 2013 Nov 1;13:95. doi: 10.1186/1471-2261-13-95.
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Cardiac myxomas: 24 years of experience in 49 patients.心脏黏液瘤:49例患者的24年经验
Eur J Cardiothorac Surg. 2002 Dec;22(6):971-7. doi: 10.1016/s1010-7940(02)00592-4.
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