Zhu Wen, Xiao Yao, Xie LinShen
West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Front Public Health. 2025 May 7;13:1592916. doi: 10.3389/fpubh.2025.1592916. eCollection 2025.
Summarize the current status, hotspots, and frontier trends in poisoning research over the past decade using CiteSpace software, and provide direction for future research in toxicology and public health.
Relevant literature published between 2015 and 2024 was retrieved from the China National Knowledge Infrastructure (CNKI) and Web of Science Core Collection. CiteSpace software was employed to conduct a visual analysis of poisoning-related research literature from the past decade.
A total of 5,644 Chinese articles and 14,985 English articles were included. High-frequency keywords in Chinese literature included "hemoperfusion" and "nursing" while high-frequency keywords in English literature included "exposure" "oxidative stress" and "identification." Keywords with strong betweenness centrality included "treatment," "blood purification" and "carbon monoxide." Recent emerging hotspots in Chinese literature were "liver function" and "oxidative stress" while in English literature, "gut microbiota" has recently gained attention.
Poisoning-related research has shown an overall upward trend. The research hotspots in this field primarily include epidemiology, oxidative stress, clinical treatment, prognosis, and chemical substances (e.g., CO, paraquat). In-depth studies on gut microbiota and oxidative stress are expected to become future research trends in this field.
运用CiteSpace软件总结过去十年中毒研究的现状、热点及前沿趋势，为毒理学和公共卫生领域的未来研究提供方向。
从中国知网（CNKI）和科学网核心合集检索2015年至2024年发表的相关文献。采用CiteSpace软件对过去十年中毒相关研究文献进行可视化分析。
共纳入5644篇中文文章和14985篇英文文章。中文文献中的高频关键词包括“血液灌流”和“护理”，而英文文献中的高频关键词包括“暴露”“氧化应激”和“识别”。中介中心性较强的关键词包括“治疗”“血液净化”和“一氧化碳”。中文文献中近期出现的热点是“肝功能”和“氧化应激”，而在英文文献中，“肠道微生物群”最近受到关注。
中毒相关研究总体呈上升趋势。该领域的研究热点主要包括流行病学、氧化应激、临床治疗、预后以及化学物质（如一氧化碳、百草枯）。对肠道微生物群和氧化应激的深入研究有望成为该领域未来的研究趋势。
