Rockland Kathleen S
Dept. Anatomy & Neurobiology, Chobanian & Avedisian School of Medicine, Boston University, 72 East Concord St., Boston, MA, 02118, USA.
Anat Sci Int. 2025 May 22. doi: 10.1007/s12565-025-00852-3.
Neuroanatomy is emerging from decades of neglect, where the synthetic approach, a neuroanatomical hallmark, was too often, as an aspersion, dismissed as "descriptive." The resurgence is in part driven by new technical advances (e.g., better visualization tools; larger sample sizes), many of which are briefly described here and treated in more detail elsewhere in this Special Issue. Another factor is the over-due recognition that a seemingly "descriptive" approach can be positively compatible with synthesis, integration, and conceptual formulation. The first two sections of this brief overview highlight advances in the level of microscopic visualization and the increasing availability of large data sets ("big data"). Illustrative examples of specific applications are drawn from the literature. A last section briefly discusses how neuroanatomy might be expected to develop further as the field continues to move forward.
神经解剖学正从数十年的被忽视状态中复苏,在过去,作为神经解剖学标志的综合方法常常被诋毁为“描述性的”而遭摒弃。这种复兴部分是由新的技术进步推动的(例如,更好的可视化工具;更大的样本量),这里简要介绍其中许多技术,本特刊其他地方会更详细地论述。另一个因素是人们终于认识到,看似“描述性”的方法实际上可以与综合、整合及概念形成积极兼容。本简要概述的前两部分重点介绍微观可视化水平的进展以及大数据集(“大数据”)越来越容易获取的情况。文中从文献中选取了具体应用的示例。最后一部分简要讨论随着该领域不断向前发展,神经解剖学有望如何进一步发展。