Hashimoto Aoba, Yotsukura Erisa, Ogawa Mamoru, Mori Kiwako, Hanyuda Akiko, Tsubota Kazuo, Kurihara Toshihide, Negishi Kazuno, Torii Hidemasa
Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Laboratory of Photobiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Sci Rep. 2025 May 22;15(1):17868. doi: 10.1038/s41598-025-02825-y.
The study goals were measurement of the choroidal thickness (CT) and investigation of related factors among children. Third-grade students at an elementary school in Tokyo participated in this study. A total of 119 schoolchildren underwent measurements of the axial length (AL), non-cycloplegic objective refraction (SE), and CT. The CT was divided into nine regions: the subfoveal area with a diameter of 1 mm (C0), a 5-mm-diameter circle-C0 (C1), and a 9-mm-diameter circle (C2); each was further divided into four quadrants. The SE, AL, and C0 CT were, respectively, - 1.57 ± 1.56 diopters, 23.39 ± 0.80 mm, and 297.73 ± 57.88 μm. Multiple regression analysis showed that the time spent using a computer was associated significantly with the CT in the C0 and the inferior C2 (C0: β = -0.728, P = 0.028; inferior C2: β = -0.527, P = 0.048), and the reading distance was associated significantly with the CT in the superior and nasal C2 (superior, β = 1.664, P = 0.007; nasal, β = 1.128, P = 0.015). In addition, time spent using smartphones, tablets, or handheld gaming devices was associated significantly with the CT in the superior and inferior C2 (superior C2: β = 0.259, P = 0.018; inferior C2: β = 0.262, P = 0.013). In conclusion, reading distance and time spent on digital devices may be associated with choroid thickness in children.
本研究的目的是测量儿童的脉络膜厚度（CT）并调查相关因素。东京一所小学的三年级学生参与了本研究。共有119名学童接受了眼轴长度（AL）、非睫状肌麻痹下客观验光（SE）和CT测量。CT被分为九个区域：直径1毫米的黄斑下区域（C0）、直径5毫米的以C0为中心的圆（C1）和直径9毫米的圆（C2）；每个区域再进一步分为四个象限。SE、AL和C0的CT分别为-1.57±1.56屈光度、23.39±0.80毫米和297.73±57.88微米。多元回归分析显示，使用电脑的时间与C0和下方C2区域的CT显著相关（C0：β=-0.728，P=0.028；下方C2：β=-0.527，P=0.048），阅读距离与上方和鼻侧C2区域的CT显著相关（上方，β=1.664，P=0.007；鼻侧，β=1.128，P=0.015）。此外，使用智能手机、平板电脑或手持游戏设备的时间与上方和下方C2区域的CT显著相关（上方C2：β=0.259，P=0.018；下方C2：β=0.262，P=0.013）。总之，阅读距离和在数字设备上花费的时间可能与儿童的脉络膜厚度有关。
