Christensson T, Hellström K, Wengle B
Eur J Clin Invest. 1977 Apr;7(2):109-13. doi: 10.1111/j.1365-2362.1977.tb01581.x.
Primary hyperparathyroidism was the most likely diagnosis in sixty-eight non-thiazide treated patients with hypercalcaemia detected in a health screening. The group included fifty-five females and thirteen males with a mean +/- SEM age of 55.0 +/- 0.7 years. On a pair basis, these patients were compared with a series of sixty-eight age- and sex-matched normocalcaemic subjects selected from the health screening register. Five subjects in each group were receiving medication for hypertension. Systolic and diastolic blood pressures were significantly higher in the hypercalcaemic subjects in the remaining fifty-eight pairs (P less than 0.001). This difference was unrelated to impaired renal filtration and many other factors associated with hypertension. It is concluded that hypercalcaemia and/or other effects of deranged parathyroid function per se may result in a blood pressure elevation on which need not necessarily attain the level of hypertension.
在一次健康筛查中检测出的68例非噻嗪类药物治疗的高钙血症患者中，原发性甲状旁腺功能亢进是最可能的诊断。该组包括55名女性和13名男性，平均年龄±标准误为55.0±0.7岁。将这些患者与从健康筛查登记册中选取的68例年龄和性别匹配的血钙正常受试者进行配对比较。每组有5名受试者正在接受高血压治疗。其余58对中，高钙血症受试者的收缩压和舒张压显著更高（P<0.001）。这种差异与肾滤过受损及许多其他与高血压相关的因素无关。结论是，高钙血症和/或甲状旁腺功能紊乱本身的其他影响可能导致血压升高，但其不一定达到高血压水平。
