Christensson T, Einarsson K
Gut. 1977 Jul;18(7):543-6. doi: 10.1136/gut.18.7.543.
The frequency of gallstone disease was studied in a group of 82 subjects (69 females and 13 males; mean ages 55-0 and 52-3 years, respectively) with verified hypercalcaemia (VHC) detected in a health screening in the Stockholm area. All non-cholecystectomised subjects were examined with a peroral cholecystography. Causes of hypercalcaemia other than primary hyperparathyroidism (PHPT) had been excluded as far as possible. Sixty-two patients had been operated upon and all but two males were found to have parathyroid adenomas. The patients were compared with a series of 82 normocalcaemic age- and sex-matched subjects, selected from the health screening register. The patients with VHC and/or PHPT had about the same frequency of gallstone disease as the controls. The results are at variance with those of other investigators who have reported that PHPT is associated with an abnormally high frequency of gallstone disease. Possible explanations of the discrepancy in results is discussed.
在斯德哥尔摩地区健康筛查中检测出确诊高钙血症（VHC）的一组82名受试者（69名女性和13名男性；平均年龄分别为55.0岁和52.3岁）中，对胆结石疾病的发生率进行了研究。所有未行胆囊切除术的受试者均接受了口服胆囊造影检查。已尽可能排除原发性甲状旁腺功能亢进症（PHPT）以外的高钙血症病因。62例患者接受了手术，除两名男性外，所有患者均发现有甲状旁腺腺瘤。将这些患者与从健康筛查登记册中选出的82名年龄和性别匹配的血钙正常受试者进行了比较。VHC和/或PHPT患者的胆结石疾病发生率与对照组大致相同。研究结果与其他研究者的结果不同，其他研究者报告称PHPT与胆结石疾病的异常高发生率有关。文中讨论了结果差异的可能解释。
