Wu Yen-Wen, Lin Wei-Wen, Lin Hung-Ju, Lin Po-Lin, Huang Li-Min, Chen Yee-Chun, Chi Hsin, Shen Ching-Fen, Lin Tsung-Hsien, Chao Ting-Hsing, Yeh Hung-I, Chen Wen-Jone, Hsieh I-Chang, Wang Jann-Tay, Chang Feng-Yee, Li Yi-Heng
Division of Cardiology, Cardiovascular Medical Center, and Department of Nuclear Medicine, Far Eastern Memorial Hospital, New Taipei City.
School of Medicine, National Yang Ming Chiao Tung University, Taipei.
Acta Cardiol Sin. 2025 May;41(3):271-287. doi: 10.6515/ACS.202505_41(3).20250407A.
Cardiovascular disease (CVD) is a leading cause of death worldwide, and infections often worsen the clinical condition of these patients. Respiratory infections, either bacterial or viral sources, are important causes of high morbidity and mortality in older adults. Beyond the burden of infection-related complications, they are also associated with non-infection-related complications such as cardiovascular (CV) events. For example, herpes zoster is associated with an increased risk of stroke and myocardial infarction. Vaccination is an effective preventive strategy for patients with CVD by reducing viral and bacterial infections, and minimizing systemic inflammatory responses to support plaque stability and reduce the likelihood of CV events in high-risk patients, thereby reducing the risks of CV and non-CV hospitalizations and mortality. Despite evidence on the effectiveness, safety, and benefits of vaccines and recommendations to vaccinate older patients and those with risk factors, vaccination rates remain sub-optimal in this population. The Taiwan Society of Cardiology and the Infectious Diseases Society of Taiwan recently appointed a task force to formulate a consensus on vaccinations for adults with high CV risk or CVD. Based on the most up-to-date information, the consensus provides current evidence-based important recommendations.
心血管疾病（CVD）是全球主要的死亡原因，感染常常会加重这些患者的临床病情。呼吸道感染，无论是细菌还是病毒引起的，都是老年人高发病率和高死亡率的重要原因。除了感染相关并发症的负担外，它们还与心血管（CV）事件等非感染相关并发症有关。例如，带状疱疹与中风和心肌梗死风险增加有关。接种疫苗是CVD患者的一种有效预防策略，可通过减少病毒和细菌感染，并尽量减少全身炎症反应来支持斑块稳定性，降低高危患者发生CV事件的可能性，从而降低CV和非CV住院及死亡风险。尽管有证据表明疫苗有效、安全且有益，也有针对老年患者和有风险因素者接种疫苗的建议，但该人群的疫苗接种率仍然不理想。台湾心脏病学会和台湾传染病学会最近任命了一个特别工作组，就高CV风险或CVD成人的疫苗接种问题达成共识。基于最新信息，该共识提供了当前基于证据的重要建议。
