Kimura Yuka, Takemoto Masanori, Nakamura Noriko, Ichinohe Takeshi, Nakakido Makoto, Iyoki Kenta, Ohta Seiichi, Miyamae Nobuhiro, Egami Yuki, Sato Koichi, Okubo Tatsuya, Tsumoto Kouhei, Wakihara Toru
Department of Chemical System Engineering, The University of Tokyo, Japan.
Institute of Engineering Innovation, The University of Tokyo, Japan.
PLoS One. 2025 May 27;20(5):e0324484. doi: 10.1371/journal.pone.0324484. eCollection 2025.
This study reports the potent antiviral ability of proton-type zeolites without the aid of any metal cations. Antiviral activities of zeolites with different topologies and chemical compositions are investigated using M13 phage and influenza virus. Proton-type zeolites exhibit excellent antiviral activity, equivalent to 99% inactivated. Antiviral tests using a centricon device suggest that direct contact of viruses on the external surface of zeolites is required to inactivate the viruses. This discovery is of importance in an interdisciplinary research field covering both zeolite science and virological science and shed light on the possibility of the development of low-cost and environmentally friendly antiviral zeolites.
本研究报告了质子型沸石在不借助任何金属阳离子的情况下具有强大的抗病毒能力。使用M13噬菌体和流感病毒研究了具有不同拓扑结构和化学组成的沸石的抗病毒活性。质子型沸石表现出优异的抗病毒活性，相当于99%的病毒被灭活。使用中空纤维超滤器进行的抗病毒测试表明，病毒需要直接接触沸石外表面才能被灭活。这一发现在涵盖沸石科学和病毒学的跨学科研究领域具有重要意义，并为开发低成本和环境友好型抗病毒沸石的可能性提供了启示。
