Collins K J, Easton J C, Belfield-Smith H, Exton-Smith A N, Pluck R A
Clin Sci (Lond). 1985 Oct;69(4):465-70. doi: 10.1042/cs0690465.
Mean deep body temperature fell by 0.4 +/- 0.1 (SD) degrees C in five sedentary, clothed 63-70 year old men and by 0.1 +/- 0.1 degrees C in four young adults after 2 h exposure in still air at 6 degrees C (P less than 0.001). The mean increase in systolic and diastolic pressure was significantly greater (P less than 0.002) in the older subjects (24 +/- 4 mmHg systolic, 13 +/- 4 mmHg diastolic) than in the young (14 +/- 6 mmHg systolic, 7 +/- 3 mmHg diastolic) after 2 h at 6 degrees C. A small rise in blood pressure occurred in the older men at 12 degrees C, but there was no increase in either group at 15 degrees C. The association of variables is particularly marked between systolic blood pressure and core temperature changes at 6 degrees C. There were no appreciable cold-adaptive changes in blood pressure or thermoregulatory responses after 7-10 days repeated exposure to 6 degrees C for 4 h each day. Blood pressure elevation in the cold was slower but more marked in the older men. These changes in blood pressure may provide a possible basis for delineating low domestic limiting temperature conditions.
5名63 - 70岁久坐不动、身着衣物的男性在6摄氏度静止空气中暴露2小时后,深部体温平均下降了0.4±0.1(标准差)摄氏度,而4名年轻人的深部体温平均下降了0.1±0.1摄氏度(P<0.001)。在6摄氏度环境下暴露2小时后,老年受试者(收缩压升高24±4 mmHg,舒张压升高13±4 mmHg)收缩压和舒张压的平均升高幅度显著大于年轻人(收缩压升高14±6 mmHg,舒张压升高7±3 mmHg)(P<0.002)。12摄氏度时老年男性血压有小幅升高,但15摄氏度时两组血压均未升高。在6摄氏度时,收缩压与核心体温变化之间的变量关联尤为明显。在每天4小时重复暴露于6摄氏度7 - 10天后,血压或体温调节反应没有明显的冷适应变化。寒冷环境中血压升高在老年男性中较慢但更明显。这些血压变化可能为确定家庭低温限制条件提供一个可能的依据。