Gellin J, Echard G, Yerle M, Dalens M, Chevalet C, Gillois M
Cytogenet Cell Genet. 1985;39(3):220-3. doi: 10.1159/000132138.
The syntenic alpha and beta casein genes were localized in the rabbit by chromosomal in situ hybridization, using a mixture of two radioactive cDNA probes corresponding to these two genes. Highly significant labeling was observed on chromosome 12. A total of 175 silver grains was found on chromosomes in the 193 mitoses studied; 18% of the grains were on chromosome 12, and 42% of the grains on this chromosome were localized to the 12q24 region. Statistical analysis revealed that this labeling was highly significant.
通过染色体原位杂交技术，使用对应这两个基因的两种放射性cDNA探针混合物，在兔中定位了同线的α和β酪蛋白基因。在12号染色体上观察到高度显著的标记。在所研究的193个有丝分裂的染色体上共发现175个银颗粒；18%的颗粒位于12号染色体上，该染色体上42%的颗粒定位于12q24区域。统计分析表明这种标记具有高度显著性。
